可持续发展目标指标3.b.3 - 对其稳定性和衡量儿童获得药物的挑战进行分析
I R Joosse1, V J Wirtz2, A T van Mourik1
1Utrecht WHO Collaborating Centre for Pharmaceutical Policy and Regulation, Division of Pharmacoepidemiology and Clinical Pharmacology, Utrecht Institute for Pharmaceutical Sciences (UIPS), Utrecht University, Universiteitsweg 99, 3584 CG, Utrecht, the Netherlands.
BMC health services research
|June 3, 2023
概括
这项研究验证了评估儿童药物可访问性的一种强有力的方法,适应了可持续发展目标 (SDG) 指标3.b.3. 结果证实了适应指标对监测儿童必需药物的可靠性.
科学领域:
- 全球健康 全球健康
- 制药政策 制药政策
- 卫生经济学 卫生经济学
背景情况:
- 可持续发展目标 (SDG) 指标3.b.3,衡量药物可访问性,对儿科患者有局限性.
- 为了解决儿童药物的这些局限性,开发了一种适应的方法.
- 本研究通过敏感性分析提供了适应方法论的稳定性的证据.
研究的目的:
- 为了验证适应的可持续发展目标 (SDG) 指标3.b.3的稳定性,用于评估儿童药物可访问性.
- 提供证据支持适应方法的可靠性,用于全球卫生监测.
- 确定有意义的评估所需的最低数量的药物.
主要方法:
- 来自10个关于儿童药物可用性和价格的历史数据集的综合数据.
- 对关键变量进行敏感性分析:治疗所需单位数量 (NUNT),疾病负担 (DB) 权重和国家贫困线 (NPL) 极限.
- 使用两个数据集评估结果:随机选择和对可用药物的偏好,比较平均设施得分.
主要成果:
- 经过调整的方法在各种场景中显示出稳定性,由于NUNT调整,平均设施得分的变化有限.
- 疾病负担加权对得分产生了重大影响,这表明需要仔细考虑.
- 通过至少12种适合儿童的药物篮获得稳定和有意义的结果.
结论:
- 适应的可持续发展目标指标3.b.3方法论是稳健的,适合纳入儿童药物获取全球指标框架.
- 建议至少有12种药物用于可靠地评估儿科药物可访问性.
- 建议在2025年框架更新中进一步审查疾病负担加权和国家贫困线考虑.
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