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儿童尾炎中的细菌腹膜炎;微生物流行病学和抗菌药物管理

Keir Bhaskar^1,2, Simon Clarke¹, Luke S P Moore^3,4,5,6

¹Chelsea and Westminster NHS Foundation Trust, 369 Fulham Road, London, SW10 9NH, UK.

Annals of clinical microbiology and antimicrobials

|June 3, 2023

概括

儿科尾切除术经常涉及Pseudomonas aeruginosa,增加了住院时间. 大肠杆菌的抗生素耐药性也会延长恢复时间,因此需要更广泛的抗菌预防尾炎与腹膜炎.

科学领域:

儿科手术儿科手术
传染性疾病传染性疾病
微生物学微生物学

背景情况:

尾炎是经常发生的儿科手术紧急情况.
经验性抗菌治疗对于预防感染并发症至关重要.
了解手术内活动的细菌病原体指导了抗微生物预防.

研究的目的:

在小儿尾切除术期间识别细菌病原体.
为了告知实证抗微生物预防策略.
分析特定病原体对患者结局的影响.

主要方法:

对小儿尾切除术患者 (18岁以下) 的回顾性分析.
从2019年11月到2022年3月的伦敦多站点医院数据.
在手术中的微生物学,停留时间 (LOS) 和抗菌疗法 (DOT) 的几天.

主要成果:

304名患者进行了尾切除;39.1%的患者进行了手术内培养.
常见的病原体:大肠杆菌 (42.0%),空气真菌 (21.0%),菌株菌株菌株菌株菌株. (14.3%) 的情况.
伪omonas spp. 这种病. 和米勒里菌株Streptococcus spp. 的种类. 与长时间的LOS相关. 48%的大肠杆菌分离物是对co-amoxiclav耐药的,从而延长了LOS.

结论:

伪omonas spp. 这种病. 在儿科尾炎中经常被隔离,与更长的住院时间相关.
肠道细菌中耐药性的演变以及 Pseudomonas spp. 的存在. 表明需要扩大抗菌覆盖范围.
针对性抗微生物预防对于儿科尾切除术至关重要,特别是腹膜炎.

关键词:

尾炎是一种尾炎.微生物学微生物学儿科儿科儿科外科手术手术手术

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