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Updated: Jul 28, 2025

Multi-photon Intracellular Sodium Imaging Combined with UV-mediated Focal Uncaging of Glutamate in CA1 Pyramidal Neurons
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Na 的结构绘图

Qiurong Wu1, Jian Huang2, Xiao Fan3

  • 1Beijing Frontier Research Center for Biological Structures, Tsinghua-Peking Joint Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing, 100084, China.

Nature communications
|June 3, 2023
PubMed
概括

这项研究揭示了使用冷EM结构的电压关闭 (Nav) 通道上的新型药物结合部位. 了解这些结合模式可以促进治疗,疼痛和心律失常的药物开发.

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