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Updated: Jul 28, 2025

Yeast As a Chassis for Developing Functional Assays to Study Human P53
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Published on: August 4, 2019

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评估轮胎的影响158 p

Shabnam Davoodi1,2, Fereidoon Daryaee1,2, James N Iuliano1,2

  • 1Center for Advanced Study of Drug Action, Stony Brook University, John S. Toll Drive, Stony Brook, New York 11794-3400, United States.

Biochemistry
|June 4, 2023
PubMed
概括

在研究Mycobacterium tuberculosis InhA时,研究人员用化物修改了活性部位氨酸158. 这表明Y158稳定了封闭的酶形式,这对于设计具有较长停留时间的新型结核病药物抑制剂至关重要.

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