老年人的焦点非性状态与意识受损:与预后相关的变量
1Postgraduate Program in Health Sciences, Pontifical Catholic University of Campinas. PUC-Campinas, Av. John Boyd Dunlop s/n - Jardim Ipaussurama, Campinas, SP, Brazil.
Epilepsy & behavior : E&B
|June 4, 2023
概括
患有焦点非状态 (fNCSE) 的老年人的预后与EEG模式有关. 横向的节律三角活动 (RDA) 和横向的周期性放电 (LPD) 表明fNCSE患者的死亡风险更高.
科学领域:
- 神经学 神经学
- 临床电生理学 临床电生理学
背景情况:
- 在老年人中,焦点非性状态与意识受损 (fNCSE) 呈现出诊断和预后挑战.
- 了解EEG特征对于预测这一脆弱人群的结果至关重要.
研究的目的:
- 研究诊断为fNCSE的老年患者的临床和EEG特征和预后之间的关系.
- 确定与fNCSE临床改善和死亡率相关的特定EEG模式.
主要方法:
- 对患有fNCSE的老年人临床变量和EEG数据的前性评估.
- 脑电图分析包括药物干预后的初始评估和治疗后评估 (24小时内).
- 使用后勤回归分析来确定与预后的关联.
主要成果:
- 在fNCSE中,形放电 (EDs) >2.5 Hz是最常见的初始EEG模式.
- 临床改善与先前的或发作史有关.
- 死亡率与横向节律三角活动 (RDA) 的存在和随后消失以及治疗后横向周期性放电 (LPDs) /EDs>2.5 Hz的存在有关.
结论:
- 在初始fNCSEEEG中,ED>2.5Hz是常见的.
- 病史预测了fNCSE的更好的临床结果.
- 特定的EEG发现,包括治疗后RDA和LPD/ED>2.5Hz,与fNCSE的老年人死亡率增加有关.
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