儿童莫亚莫亚的发作:危险因素和功能结果
John R Gatti1, Rachel Penn2, Syed Ameen Ahmad1
1Johns Hopkins School of Medicine, Baltimore, Maryland.
Pediatric neurology
|June 4, 2023
概括
在患有莫亚莫亚的儿童中,年龄较小和症状呈现增加了发作风险. 发作与较差的神经结果相关,强调需要进一步研究管理策略.
科学领域:
- 儿科神经学 儿科神经学
- 神经血管疾病 神经血管疾病
- 发病学 (Epileptology) 是一个专业的学科.
背景情况:
- 儿童的莫亚莫亚动脉病症具有严重的中风和发作的风险.
- 影响发育的因素及其对神经结果的影响仍然不太清楚.
研究的目的:
- 为了确定儿科莫亚莫亚患者发作的危险因素.
- 在这个人群中调查发作和功能结果之间的关联.
主要方法:
- 在2003年至2021年期间评估的84名莫亚莫亚儿童的回顾性队列研究.
- 分析了发作发生率和功能结果 (儿科中风结果测量).
- 后勤回归模型评估了临床变量,发作发生和结果之间的关联.
主要成果:
- 34%的儿童经历了发作,莫亚莫亚病和基线心脏病发作是显著的危险因素.
- 呈现时的年龄较大和无症状发作与发作的可能性较低有关.
- 发作与更糟糕的功能结果 (PSOM分数) 有显著的关联.
结论:
- 较年轻,有症状的儿童患有moyamoya更容易发作.
- 发作会对儿科莫亚莫亚患者的功能结果产生负面影响.
- 需要进一步的前性研究来了解的影响和治疗疗效.
更多相关视频
09:57Author Spotlight: Advancing Pediatric Epilepsy Surgery in Children Through Novel Biomarkers and Enhanced Localization
Published on: September 20, 2024
2.7K
10:22Interictal High Frequency Oscillations Detected with Simultaneous Magnetoencephalography and Electroencephalography as Biomarker of Pediatric Epilepsy
Published on: December 6, 2016
20.4K
相关概念视频
Seizures: Classification
445
Epilepsy is primarily characterized by unpredictable seizures, either provoked by an identifiable factor, such as injury or illness, or unprovoked, occurring spontaneously without apparent cause.
Seizures are typically classified into two main categories: focal and generalized seizures.
Focal Seizures
Focal seizures originate from specific regions of the brain. These seizures are further sub-classified into two types:
Seizures are typically classified into two main categories: focal and generalized seizures.
Focal Seizures
Focal seizures originate from specific regions of the brain. These seizures are further sub-classified into two types:
445
Epilepsy and Seizures: Overview
230
Epilepsy is a chronic neurological disease marked by recurrent, unpredictable seizures. These seizures are caused by abnormal electrical discharges in the brain, leading to behavior, sensation, or consciousness alterations. They can also cause transient impairment of awareness, interfering with daily activities.
Various factors can trigger epilepsy, including genetic factors, brain damage, metabolic causes, and unknown etiology. Diagnosis of epilepsy involves electroencephalography (EEG), which...
Various factors can trigger epilepsy, including genetic factors, brain damage, metabolic causes, and unknown etiology. Diagnosis of epilepsy involves electroencephalography (EEG), which...
230
Aneurysm II: Clinical Manifestations and Diagnostic Studies
11
Thoracic, aortic arch and abdominal aneurysms are significant vascular conditions that can present with various clinical manifestations and lead to serious complications. Understanding these manifestations and the appropriate diagnostic studies is essential for effective management and treatment.Thoracic Aortic AneurysmsThoracic aortic aneurysms often remain asymptomatic until they reach a size that impinges on adjacent structures. They typically cause deep, diffuse chest pain that radiates to...
11
