在遵循非常低热量饮食后,定义生理症
Taha Mollah1, Carla Gillespie1, Anthony Cocco1
1Department of Upper GI and Hepatobiliary Surgery, St. Vincent's Hospital, Melbourne, Australia.
The Journal of surgical research
|June 4, 2023
概括
非常低热量饮食 (VLCDs) 显著增加水平,并可能导致手术后的代谢酸症. 这对于使用SGLT2抑制剂的糖尿病患者的监测至关重要.
科学领域:
- 代谢手术 代谢手术
- 减肥医学 减肥医学
- 手术营养是指手术营养.
背景情况:
- 非常低热量饮食 (VLCD) 在腹代谢手术中被用于术前,可能会诱导生理症.
- 优糖性酸性是糖尿病患者在接受手术时服用-葡萄糖-携带载体-2 抑制剂 (SGLT2i) 的新出现的并发症.
- 在这些患者中,VLCD诱导的症可能会使水平的监测复杂化.
研究的目的:
- 评估手术前VLCD与标准禁食相比对外科手术期间水平的影响.
- 评估VLCD在外科手术期间对酸平衡的影响.
主要方法:
- 一项前性研究涉及27名VLCD患者和26名接受手术的对照患者.
- 排除标准包括糖尿病和SGLT2i使用.
- 在术前进行了和酸测量,使用单变量和多变量回归 (P < 0.005) 进行统计分析.
主要成果:
- 接受VLCD治疗的患者在手术前,手术后立即和手术后的第一天 (P < 0.001) 呈现出明显更高的基水平的中位数.
- 在VLCD患者中,术后立即出现了代谢性化症 (pH 7.29与7.35,P = 0.019),在术后第一天正常化.
- 在手术前的酸平衡在两组都是正常的.
结论:
- 手术前的VLCD增加了手术前的水平,手术后的值类似于代谢性酸性脂肪酸.
- 这些发现需要仔细考虑,特别是在使用SGLT2抑制剂监测糖尿病患者时.
- 由VLCD诱导的症可能会影响外科手术期间的代谢监测.
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