通过衰竭的血静态悖论进行导航:一个实际的概述
Jessica Caruana1, Nicoletta Riva2, Kevin Vella3
1Department of Applied Biomedical Science, Faculty of Health Sciences, University of Malta, Msida, Malta.
British journal of haematology
|June 4, 2023
概括
患有慢性病 (CKD) 的患者面临出血和血栓形成的高风险. 本综述探讨了末期脏疾病中血液静止的科学,并指导了对这些复杂的出血和凝血挑战的管理.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 血液学 血液学 血液学
- 内部医学 内部医学
背景情况:
- 慢性病 (CKD) 影响全球9.1%,对健康造成重大负担.
- 患有CKD的患者,尤其是透析患者,有双重的出血和血栓形成风险.
- 有限的临床证据表明,在这个脆弱人群中,治疗静血症的挑战是有限的.
研究的目的:
- 审查目前对末期脏疾病 (ESKD) 中血静的理解.
- 将基础科学知识转化为临床实践,用于治疗慢性病患者的出血和血栓形成.
- 为最佳的患者管理提供基于证据的指导.
主要方法:
- 关于ESKD中血液静止的基础科学原理的文献综述.
- 对治疗慢性病患者出血和血栓形成的临床挑战的分析.
- 综合现有证据和临床指南.
主要成果:
- 详细解释ESKD中复杂的静血异常.
- 鉴定慢性病患者面临的常见血静性挑战.
- 对抗血小板和抗凝剂使用的有限但可用的证据的讨论.
结论:
- 慢性病患者具有独特且同时存在的出血和血栓形成风险.
- 更深入地了解ESKD中的静血对于有效的临床管理至关重要.
- 需要进一步的研究和明确的指导方针来优化这些患者的治疗.
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