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Updated: Jul 28, 2025

Author Spotlight: Investigating the Relationship Between FSH and Pathophysiological Changes in Perimenopausal Women - Insights from a Mouse Model
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在骨质疏松症上基因预测的循环血清同型半氨酸水平:一项两样本的门德尔随机化研究

ChenYu Wang1, Xiang Zhang2, Bo Qiu3

  • 1Department of Orthopedics, Renmin Hospital of Wuhan University, Wuhan, China.

Scientific reports
|June 4, 2023
PubMed
概括

这项研究发现,较高的血清homocysteine (Hcy) 水平可能会对欧洲人的脚骨矿物质密度 (H-BMD) 产生因果影响. 然而,在Hcy和整体骨质疏松症风险之间没有发现因果关系.

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Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
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Cardiac biomarkers are critical in diagnosing, prognosing, and managing cardiovascular diseases. Routine measurement of specific biomarkers such as B-type natriuretic peptide (BNP), C-reactive protein (CRP), and homocysteine (Hcy) is common practice in clinical settings to evaluate heart function and predict cardiovascular events.
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Natriuretic Peptides (BNP)
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Study Designs in Epidemiology

Epidemiological study designs are fundamental tools for investigating the distribution, determinants, and control of health conditions in populations. They help researchers understand the relationships between exposures and outcomes, and they broadly fall into two categories: "observational" and "experimental" studies.
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Bone Remodeling01:40

Bone Remodeling

Bone remodeling is a continuous and balanced process of bone resorption by osteoclasts and bone formation by osteoblasts. In adults, it helps maintain bone mass and calcium homeostasis. While mechanical stress can stimulate turnover as part of the normal maintenance and reparative process, several hormones also regulate bone remodeling.
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The growth and maintenance of bone are regulated by a combination of nutritional factors, including vitamins, such as vitamin A, B12, C, D, and K.
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