与COVID-19感染相关的肺血栓塞栓性疾病:老年和非老年人群之间的比较
T L Tan1, N E Illa2, S Y Ting3
1Hospital Tengku Ampuan Rahimah, Internal Medicine Department, Selangor, Malaysia. tanthailun@gmail.com.
The Medical journal of Malaysia
|June 4, 2023
概括
患有2019年新冠病毒病 (COVID-19) 和肺血栓塞栓性疾病的老年患者面临更高的死亡风险. 这项研究发现,尽管老年人早些时候出现了这种疾病,但他们的疾病更严重,结果更差.
科学领域:
- 医学 医学 医学 医学 医学
- 老年学是一门学科.
- 放射学 放射学是一门学科.
背景情况:
- 冠状病毒疾病2019 (COVID-19) 感染在老年人中越来越多.
- 肺性血栓栓塞 (PTE) 疾病是COVID-19已知的并发症之一.
- 了解老年和非老年患者之间COVID-19相关PTE的差异至关重要.
研究的目的:
- 为了比较COVID-19患者中PTE的临床和计算机断层扫描 (CT) 特征.
- 探索PTE的老年与非老年COVID-19患者的60天死亡率.
- 在老年COVID-19患者中确定与PTE相关的风险因素和结果.
主要方法:
- 追溯的横截面研究.
- 包括2021年4月至5月入院的同时患有COVID-19和PTE疾病的患者.
- 对人口统计,临床,实验室和CT肺血管造影 (CTPA) 数据的分析.
主要成果:
- 在老年人队伍中,高血压,糖尿病和脂质失调的患病率更高.
- 老年患者的淋巴细胞和白蛋白水平较低,尽管早期出现了更严重的疾病.
- 在这两组中,肺血栓主要发生在细分/亚细分动脉中,老年人住院死亡率明显较高.
结论:
- 患有COVID-19和PTE的老年患者的死亡率更高,生存概率更差.
- 在老年人中,典型的COVID-19症状可能会被掩盖,可能会延迟诊断并增加不良结果.
- 在老年COVID-19患者中迅速识别和管理PTE对于改善结果至关重要.
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