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Updated: Jul 28, 2025

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抗亡蛋白BCL-XL作为胃癌的治疗脆弱性

Yumin Wei1,2,3, Liping Zhang1,2,3, Chao Wang1,2,3

  • 1National Human Diseases Animal Model Resource Center, The Institute of Laboratory Animal Science, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.

Animal models and experimental medicine
|June 5, 2023
PubMed
概括

胃癌 (GC) 细胞可以通过抑制BCL-XL来向,BCL-XL是一种对其生存至关重要的蛋白质. 高水平的BCL-XL蛋白质,而不是基因拷贝数,预测治疗反应,确定BCL-XL作为一个有前途的治疗点在GC.

关键词:
在BCL2L1 (BCL-XL) 中.这就是PROTAC-BCL-XL.灭症 (apoptosis) 是一种死亡的过程.胃癌 (GC) 是一种胃癌.有选择性的BCL-XL抑制剂.

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