一种新型仿生材料的重矿化潜力 (自组合P)
Shruti Satish Shetty1, Sridhar Nekkanti2
1Department of Pediatric and Preventive Dentistry, Manipal College of Dental Sciences, Manipal Academy of Higher Education, Manipal, Karnataka, India.
The journal of contemporary dental practice
|June 5, 2023
概括
与化漆相比,自我组装的P11-4显示出更高的重矿化潜力,显示出更大的和的矿物质收益. 这种提供了一个有前途的,不那么侵入性的替代方案,用于治疗早期的膜病变.
科学领域:
- 生物材料科学 生物材料科学
- 牙科研究 牙科研究
- 纳米技术 纳米技术
背景情况:
- 早期的牙质病变,或白斑病变 (WSL),在修复性牙科中是一个重大挑战.
- 目前的治疗方法通常涉及侵入性手术或以化物为基础的疗法,有效性各不相同.
- 自组装为生物仿真重矿化提供了一种新的方法.
研究的目的:
- 为了评估自我组装P11-4 (Curodont RepairTM) 与标准化物漆 (Bifluorid 10®) 相比的重矿化功效.
- 用于量化矿物质收益,特别是,和化物,经过处理两种药物后.
- 评估P11-4作为化物替代品的潜力,用于质重矿化.
主要方法:
- 使用了20个表面完好无损的提取前,其中一半经过了去矿化.
- 脱矿部分用P11-4或化物漆处理,并在人工唾液中化21天.
- 用DIAGNOdentTM笔,ICDAS-II评分和扫描电子显微镜-能量分散X射线 (SEM-EDX) 分析来评估重矿化.
主要成果:
- 经过重矿化后的DIAGNOdentTM和ICDAS-II得分表明,在组之间存在统计学上显著的差异.
- SEM-EDX分析显示,与双化物10®相比,Curodont RepairTM (P11-4) 的和平均值显著更高.
- 双化物10®的化物吸收率高于Curodont RepairTM.
结论:
- 自组合P11-4表现出优越的重矿化潜力比化漆在初始的面膜损伤.
- P11-4促进和的更大增长,这是乳液修复所必需的矿物质.
- P11-4代表了一种新的,最少的侵入性治疗选择,用于管理早期牙损伤.
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