干预导致水母刺伤的症状和迹象的干预措施
Richard G McGee1,2, Angela C Webster3, Sharon R Lewis4
1The University of Newcastle Central Coast Clinical School, Gosford Hospital, Gosford, Australia.
The Cochrane database of systematic reviews
|June 5, 2023
概括
由于有限的,低确定性证据,水母治疗的有效性仍然不确定. 这次审查没有发现热与冷的应用或用于水母中毒疼痛缓解的局部治疗有明确的益处.
科学领域:
- 海洋毒理学 海洋毒理学
- 皮肤病学 皮肤病学
- 紧急医疗 紧急医疗
背景情况:
- 水母中毒是沿海地区常见的现象,刺的严重程度因物种而异.
- 刺痛会引起疼痛,皮肤反应,以及潜在的严重系统性影响,如伊鲁坎吉综合征.
- 针对水母刺伤的建议治疗方法的有效性尚未得到充分证实.
研究的目的:
- 评估干预措施对成人和儿童的水母刺伤的益处和危害.
- 根据随机和准随机试验的证据来评估治疗方法.
主要方法:
- 搜索了多个数据库 (CENTRAL,MEDLINE,Embase,Web of Science) 和临床试验注册到2022年10月.
- 包括随机对照试验 (RCT) 和准RCT,比较干预与安慰剂或没有治疗.
- 分析了9项研究 (六项RCT,3项准RCT) 涉及574名参与者,重点关注热与冷应用和局部治疗.
主要成果:
- 对所有结果的证据的确定性非常低,这使得很难确定治疗的有效性.
- 不确定性存在于热或冷的应用是否为Physalia或盒子水母刺痛提供显著的疼痛减轻.
- 局部应用也显示了缓解疼痛的证据确定性非常低; 一项研究报告说,氨治疗导致烧伤.
结论:
- 只有少数研究提供了数据,这些数据因治疗类型,环境和水母物种而异.
- 由于证据的确定性非常低,无法确定对水母刺痛的评估治疗方法的有效性.
- 这些发现与之前的审查一致,突出了对水母刺治疗方法持续缺乏确的证据.
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