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Updated: Jul 28, 2025

Gene Digital Circuits Based on CRISPR-Cas Systems and Anti-CRISPR Proteins
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通过结构比较来寻找抗CRISPR蛋白的起源

Harutyun Sahakyan1, Kira S Makarova1, Eugene V Koonin1

  • 1National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, Maryland, USA.

The CRISPR journal
|June 5, 2023
PubMed
概括

许多病毒抗CRISPR蛋白 (Acrs) 的结构建模以了解它们的起源. 研究人员确定了潜在的祖先蛋白质,揭示了毒素-抗毒素和SOS修复系统对抗CRISPR功能的招募.

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