呼吸机相关肺炎中的抗菌素耐药性:预测性微生物学和基于证据的治疗方法
1Department of Microbiology, College of Medicine, King Fahad Hospital of the University, Imam Abdulrahman Bin Faisal University, Dammam, Kingdom of Saudi Arabia. amalnimr@iau.edu.sa.
Infectious diseases and therapy
|June 5, 2023
概括
呼吸机相关肺炎 (VAP) 是一个关键的ICU感染. 本综述详细介绍了抗微生物药物耐药性风险因素,诊断工具和VAP的管理策略,重点是格兰氏阴性病原体.
科学领域:
- 关键护理医学 关键护理医学
- 传染性疾病 传染性疾病
- 微生物学 微生物学
背景情况:
- 呼吸机相关肺炎 (VAP) 是常见且严重的重症监护室 (ICU) 感染.
- VAP对抗生素使用做出了重大贡献,并且具有很高的可归因死亡率,特别是在抗菌素耐药性方面.
- 有效的抗微生物治疗和微生物诊断对于管理VAP至关重要.
研究的目的:
- 审查成年VAP中抗菌素耐药性的危险因素.
- 讨论VAP的新型微生物诊断工具.
- 总结基于证据的抗微生物管理和药物耐药VAP的预防策略.
主要方法:
- 文献综述侧重于VAP,抗菌素耐药性和格拉姆阴性病原体.
- 对抗性机制和诊断方法的现有证据的分析.
- 探索VAP预测微生物学新兴概念的探索.
主要成果:
- 抗多种药物格拉姆阴性细菌是VAP的一个重要问题.
- 针对VAP的最佳微生物采样和测试仍然是正在进行的研究领域.
- 强调了基于证据的策略,用于管理和预防耐药VAP.
结论:
- 了解抗菌素耐药性机制和及时使用微生物诊断对于有效的VAP治疗至关重要.
- 积极的管理和预防对于打击耐药VAP日益增长的威胁至关重要.
- 该审查还涉及COVID-19和预测微生物学背景下的VAP.
更多相关视频
相关概念视频
Pneumonia IV: Management
402
The treatment of pneumonia varies based on its severity and the causative pathogen. Here is a structured approach to managing pneumonia, integrating pharmaceutical and supportive care strategies.
Bacterial Pneumonia Treatment
For bacterial pneumonia, antibiotics serve as the cornerstone of therapy. Initial treatment often begins with empirical antibiotics, tailored to the anticipated causative organism and adjusted based on culture results. Key antibiotic choices include:
Bacterial Pneumonia Treatment
For bacterial pneumonia, antibiotics serve as the cornerstone of therapy. Initial treatment often begins with empirical antibiotics, tailored to the anticipated causative organism and adjusted based on culture results. Key antibiotic choices include:
402
Pneumonia V: Nursing management and Prevention
2.2K
Nursing management of pneumonia involves promoting airway patency, facilitating rest and conserving energy, encouraging fluid intake, maintaining nutrition, and educating patients.
The nurse must practice strict medical asepsis and adhere to infection control guidelines to minimize healthcare-associated infections.
Enhance airway patency
Position the patient correctly to facilitate drainage of the affected lung segments. Manual or mechanical percussion and vibration can also be employed....
The nurse must practice strict medical asepsis and adhere to infection control guidelines to minimize healthcare-associated infections.
Enhance airway patency
Position the patient correctly to facilitate drainage of the affected lung segments. Manual or mechanical percussion and vibration can also be employed....
2.2K
Pneumonia I: Introduction
287
Pneumonia is an acute respiratory infection that targets the lungs, specifically the alveoli. These tiny air sacs, essential for oxygen exchange, become engorged with pus and fluid, severely hindering breathing, decreasing oxygen absorption, and causing significant pain and discomfort during respiration.
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
287
Pneumonia III: Complications and Assessment
287
Pneumonia poses the potential for numerous complications that warrant consideration. These complications include the following:
287
Acute Respiratory Failure-V
169
The treatment for acute respiratory failure varies based on factors like the underlying cause, overall health, and severity. A collaborative healthcare team is essential for early detection, often through arterial blood gas analysis. Identifying the cause is the primary goal, with treatment strategies adjusted for ventilation/perfusion (V/Q) mismatch, shunting, or diffusion impairment.
Ensure that patients are monitored continuously for their response to therapy, including changes in...
Ensure that patients are monitored continuously for their response to therapy, including changes in...
169
Mechanical Ventilation I: Indication and Settings
549
Mechanical ventilation is a life-saving technique for managing acute respiratory failure and other respiratory complications. The process involves using a machine known as a ventilator to supply oxygen to the lungs and assist in removing carbon dioxide. It serves as a bridge to long-term mechanical ventilation or a temporary measure until ventilatory support is discontinued. The ventilator can maintain this function for a prolonged period, providing critical support for patients until they can...
549


