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Updated: Jul 28, 2025

High-throughput Quantitative Real-time RT-PCR Assay for Determining Expression Profiles of Types I and III Interferon Subtypes
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人类RELA主导-阴性突变是I型干扰因子病的基础,具有自身炎症和自身免疫力

Kunihiko Moriya1, Tomohiro Nakano1, Yoshitaka Honda2,3,4

  • 1Department of Pediatrics, Tohoku University Graduate School of Medicine, Sendai, Japan.

The Journal of experimental medicine
|June 5, 2023
PubMed
概括

在NF-κB通路中的遗传缺陷,特别是RELA突变,导致一种新的自身炎症性疾病. 这种情况导致I型干扰素的过度产生,引发全身自身免疫和自身炎症症状.

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