空间疏忽治疗的最新进展:网络和神经心理学
Alex R Carter1, A M Barrett2,3
1Department of Neurology, Department of Orthopedic Surgery, Washington University in St. Louis School of Medicine, St. Louis, MO, USA.
Expert review of neurotherapeutics
|June 5, 2023
概括
空间疏忽是一种常见的中风后果,正通过脑网络研究得到更好的理解. 针对这些网络的神经调节疗法为中风幸存者提供了有希望的个性化治疗方法.
科学领域:
- 神经科学是一个神经科学.
- 康复医学 康复医学 康复医学
- 认知科学 认知科学
背景情况:
- 空间疏忽是中风后的常见和致残的疾病.
- 了解空间认知的神经支对于开发有效治疗方法至关重要.
- 目前的治疗策略正在通过机械方法来改进.
研究的目的:
- 审查神经调节策略来治疗中风后的空间疏忽.
- 探索不同治疗方法所针对的大脑网络机制.
- 突出需要改进分类和个性化治疗的需要.
主要方法:
- 对空间疏忽的基于证据的神经调节技术的审查.
- 对认知策略,视觉运动适应,非侵入性脑刺激和药物调节的分析.
- 检查每个治疗方法中涉及的大脑网络.
主要成果:
- 不同的疗法针对与空间认知有关的独特的大脑网络.
- 认知策略影响前线执行网络.
- 视觉运动适应涉及体和前额体连接,特别是针对忽视.
- 非侵入性脑刺激通过体连接调节半球间活动.
- 药物治疗可以利用右侧激发网络.
结论:
- 试验中的方法异质性使得最终结论变得复杂.
- 分类空间疏忽对于推进研究和临床实践至关重要.
- 了解治疗机制-亚型相互作用将使空间疏忽的精准医学成为可能.
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