2型糖尿病是精神疾病的潜在,并发症或后果状态
Milica M Borovcanin1, Katarina Vesic2, Ivica Petrovic3
1Department of Psychiatry, Faculty of Medical Sciences, University of Kragujevac, Kragujevac 34 000, Serbia. milicaborovcanin@yahoo.com.
World journal of diabetes
|June 5, 2023
概括
2型糖尿病 (T2DM) 和精神障碍经常同时发生,共享复杂的双向联系. 了解这些联系,包括免疫功能障碍和肠-大脑信号,对于综合治疗方法至关重要.
科学领域:
- 神经科学是一个神经科学.
- 内分泌学 在内分泌学.
- 精神病学是一个精神病学.
背景情况:
- 身体和精神疾病往往并存,带来临床挑战.
- 全球2型糖尿病 (T2DM) 患病率正在上升,与精神疾病的共同发病率很高.
- 双向关系T2DM和精神障碍是复杂的,并没有完全理解.
研究的目的:
- 审查关于T2DM和精神障碍之间的共享病原性途径的当前数据.
- 强调这些并发症的复杂联系和复杂性.
- 在这些条件的背景下,专注于认知表现和神经退行.
主要方法:
- 关于T2DM和精神疾病并发症的最新研究的文献综述.
- 分析共享机制,包括免疫/炎症功能障碍,氧化应激和内皮功能障碍.
- 探索肠-大脑轴及其在调节新陈代谢和认知中的作用.
主要成果:
- 共同的途径包括免疫功能障碍,氧化应激,内皮功能障碍和代谢障碍.
- T2DM是认知能力下降的危险因素,可能导致痴呆.
- 肠-大脑信号通路影响食欲和葡萄糖的产生,提供治疗途径.
结论:
- 综合治疗方法对于管理并发性T2DM和精神障碍至关重要.
- 由于这些疾病的复杂性,需要个性化治疗策略.
- 对共享机制,特别是肠-大脑轴的进一步研究是有必要的.
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