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初步怀疑的过敏反应在化对比之后:在一个没有甲状腺功能障碍史的73岁女性中发生了基于的现象
Devina Adalja1, Brooke E Kania1, Isaac M Soliman2
1Internal Medicine, St. Joseph's Medical Center, Paterson, USA.
Cureus
|June 5, 2023
概括
诱导的甲状腺功能障碍,或Jod-Basedow现象,可以发生在医学成像后. 临床医生应该意识到这种罕见的疾病,以防止敏感患者不必要暴露于.
科学领域:
- 内分泌学 在内分泌学.
- 放射学 放射学是一门学科.
- 内部医学 内部医学
背景情况:
- 约德-贝塞多现象 (JB现象) 或诱导的甲状腺功能障碍是一种罕见的疾病.
- 放射性成像中使用的有的对比剂可以含有大量的,可能会在无甲状腺患者中引发甲状腺功能障碍.
- 以前存在的甲状腺疾病,富含的食物和某些药物 (例如,阿米奥达龙) 会增加患JB现象的风险.
研究的目的:
- 在没有先前甲状腺功能障碍的患者中报告诱导的甲状腺功能障碍病例.
- 突出临床医生对JB现象的认识的重要性,以预防阳性发炎毒性病.
- 讨论JB现象的病理生理学,强调过度暴露和自我调节受损的作用.
主要方法:
- 病例报告详细介绍了一名73岁的女性患者.
- 对临床表现的审查,包括因肺炎炎入院和随后因疑似过敏反应转移到ICU.
- 分析离子对比剂的使用与甲状腺功能增强症的发展之间的潜在联系.
主要成果:
- 患者在暴露于有的对比剂后出现了临床显著的甲状腺功能过高.
- 这一案例表明,JB现象甚至可以发生在没有甲状腺功能障碍史的人身上.
- 过度的负荷压倒了甲状腺的调节机制,导致甲状腺毒性.
结论:
- 约德-贝塞多现象是接受类对比剂的患者的关键考虑因素,特别是那些患有微妙或未被诊断的甲状腺异常的患者.
- 临床医生必须对诱导的甲状腺功能障碍的迹象保持警,以避免误诊并确保适当的管理.
- 对此类事件的认识和报告对于患者的安全和优化使用含对比剂至关重要.
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