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使用risedronate可能会减轻尾肌瘦质量损失二次袖子胃切除术:来自试点随机对照试验的结果

Laura E Flores¹, Kristen M Beavers², Daniel P Beavers³

¹College of Allied Health Professions, University of Nebraska Medical Center, Omaha, NE, USA.

JCSM rapid communications

|June 5, 2023

概括

瑞斯德罗纳酸可能有助于在袖子胃切除术 (SG) 后保持瘦肉量. 这项试点研究表明,瑞塞德酸盐可以减轻SG后尾性瘦肉质量损失,这需要进一步调查.

科学领域:

腹腔外科手术的结果
代谢健康和身体组成

背景情况:

袖子胃切除术 (SG) 导致显著的减肥和心脏代谢益处.
然而,SG后的瘦肉质量损失会给健康带来风险.
双酸盐正在被探索,作为一种潜在的干预措施来保护瘦肉质量.

研究的目的:

调查瑞塞德龙酸与安慰剂对SG后瘦体质变化的作用.
通过使用双能量X射线吸收计 (DXA) 和计算机断层扫描 (CT) 在12个月内评估瘦肉质量的变化.

主要方法:

一个随机对照试验,涉及24名SG患者.
参与者接受了六个月的口服瑞塞德酸盐或安慰剂.
在基线,六个月和12个月使用DXA和CT测量身体成分.

主要成果:

虽然两组都经历了体重减轻,但在六个月后,瑞塞德酸盐显示了节省尾肌肉量的趋势.
12个月后,瑞塞德酸盐组从基线保持了尾肌肉质量.
相比之下,安慰剂组在12个月后表现出显著的尾瘦肉质量损失.

结论:

试验数据表明,瑞塞德龙酸治疗可能有助于减轻SG后尾肌瘦质量损失.
需要进一步的研究来证实这些发现并确定临床疗效.

关键词:

抗吸收剂是一种抗吸收剂.减肥手术减肥手术是什么身体构成身体组成临床试验中的临床试验.双能X射线吸收计二重能量X射线吸收计瘦身质量瘦身质量瘦身质量减肥减肥减肥减肥减肥减肥

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