透导管大动脉置换相关的传染性内心炎:早期,中期和晚期发病病例的比较
Simrat Kaur1, Gursharan Singh Samra1, Manpreet Kaur2
1Department of Internal Medicine, Cleveland Clinic, Cleveland, Ohio, USA.
Structural heart : the journal of the Heart Team
|June 5, 2023
概括
超导管大动脉置换相关的传染性内心炎 (TAVR-IE) 最常见的是中间发生. 金黄色葡萄球菌是主要的病原体,晚期发病的TAVR-IE的死亡率为100%.
科学领域:
- 心脏病学 心脏病学
- 传染性疾病 传染性疾病
- 医疗器械并发症 医疗器械并发症
背景情况:
- 通过导管的大动脉置换相关的传染性内心炎 (TAVR-IE) 是一种罕见但严重的并发症.
- 早期,中期和晚期发作的TAVR-IE的特征仍然不太清楚.
研究的目的:
- 调查TAVR-IE的风险因素,微生物学,诊断和治疗.
- 根据发病时间分析TAVR-IE:早期 (<60天),中期 (60-365天) 和晚期 (>1年).
主要方法:
- 从传染性内心炎注册表 (2007-2019) 中对TAVR-IE病例的回顾性分析.
- 数据收集包括患者的人口统计,胸腔外科医生协会风险评分,致病生物,诊断方法 (包括18-氧葡萄糖正子发射断层扫描),管理和结果.
主要成果:
- 确定了十个TAVR-IE病例. 大多数患者 (60%) 呈现中期发病.
- 金黄色葡萄球菌是最常见的病原体 (66.6%).
- 总的来说,死亡率为40%,早期/中期组为25%,晚期发病组为100%. 保守管理是常见的,生存率为37.5%.
结论:
- 中期发病是TAVR-IE最常见的表现.
- 金黄色葡萄球菌是主要的病原体.
- TAVR-IE发病的时间显著影响预后,晚发病在这个队列中均致命.
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