在服用苏加马德克斯后心脏骤停
A V Pereira1, R R Oliveira1, C Esteves1
1Department of Anesthesiology Hospital Vila Franca de Xira EPE Vila Franca de Xira Portugal.
Anaesthesia reports
|June 5, 2023
概括
手术后的苏加马德克斯 (Sugammadex) 给药可能会导致患者严重的胸肌梗塞和心脏骤停. 这份病例报告强调了这种常用的麻醉逆转剂的潜在严重并发症.
科学领域:
- 麻醉学 麻醉学
- 药理学 药理学是指药理学的学科.
- 关键护理医学 关键护理医学
背景情况:
- 苏加马德克斯是一种神经肌肉阻塞的逆转剂.
- 胸和心脏骤停是罕见的,但与sugammadex相关的严重不良事件.
- 苏加马德克斯诱导的心血管事件的确切机制尚不清楚.
研究的目的:
- 在服用苏加马德克斯后报告心脏骤停的情况.
- 讨论sugammadex与导致心脏骤停的严重心肌梗塞之间的潜在联系.
- 为了提高人们对这种潜在并发症的认识.
主要方法:
- 一个68岁的男性接受选项修复的案例报告.
- 用于肌肉放松的罗库和用于逆转的sugammadex.
- 血液动力学参数的监测和对复苏的反应.
- 复苏后的调查,包括血清三酶水平.
主要成果:
- 患者在sugammadex后出现了严重的胸肌梗塞和低血压,耐药于以弗德林.
- 进展到无脉动电活动的心脏骤停,需要心肺复苏.
- 自发循环的恢复在4分钟后实现.
- 逮捕后的调查在很大程度上是不起眼的,没有明确的替代原因被确定.
结论:
- 苏加马德克斯可能导致严重的胸肌梗塞和心脏骤停.
- 时间关联和临床过程表明sugammadex是可能的病因.
- 对于使用sugammadex的临床医生来说,提高对这种不良事件的认识至关重要.
相关概念视频
Cardiopulmonary Resuscitation IV: Pharmacological Management
29
Pharmacologic intervention is crucial in treating cardiac arrest patients during ACLS or Advanced Cardiovascular Life Support. The ACLS algorithms guide the administration of specific drugs based on the patient's cardiac arrest rhythm, which includes pulseless ventricular tachycardia (VT), ventricular fibrillation (VF), asystole, and pulseless electrical activity (PEA).EpinephrineIndication: Epinephrine is the first-line drug for all cardiac arrest rhythms.Mechanism of Action: Epinephrine...
29
Introduction Cardiac Emergencies
36
Cardiac emergencies are critical situations involving the heart that require immediate medical intervention to prevent severe complications or death. These emergencies often arise from underlying heart conditions that impair the heart's ability to function correctly.Types of Cardiac EmergenciesThe most common types of cardiac emergencies include Acute Coronary Syndrome (ACS), myocardial infarction (MI), cardiac arrest, and heart failure.Acute Coronary Syndrome (ACS)Acute Coronary Syndrome (ACS)...
36
Cardiopulmonary Resuscitation I: Adult
22
Cardiopulmonary resuscitation, or CPR, is a life-saving emergency procedure performed when a person's heart has stopped beating or they are no longer breathing. The foundation of CPR is Basic Life Support (BLS), which focuses on the early recognition of cardiac arrest, the immediate start of high-quality chest compressions, and the timely use of an automated external defibrillator (AED).Assessing Responsiveness and Checking the Carotid PulseWhen approaching an unresponsive person, first ensure...
22
Cardiopulmonary Resuscitation III: AED Use
42
Introduction to AEDAn Automated External Defibrillator (AED) is a portable medical device that analyzes the heart's rhythm and, if necessary, delivers an electrical shock to help the heart re-establish an effective rhythm during sudden cardiac arrest (SCA). SCA occurs when the heart suddenly and unexpectedly stops beating, leading to a loss of blood flow to the brain and other vital organs. In such emergencies, time is of the essence, and using an AED, combined with Cardiopulmonary...
42
Depolarizing Blockers: Pharmocokinetics
353
Depolarizing blockers are administered through intravenous injection. Succinylcholine is the most common choice of depolarizing blockers in emergency clinical practices. Although they have a rapid onset, they readily diffuse away from the motor end plate into the extracellular fluid. They are metabolized by enzymes such as liver butyrylcholinesterase and plasma pseudocholinesterases. This produces a short duration of action, typically 5-10 minutes long, unlike nondepolarizing blockers, which...
353
Skeletal Muscle Relaxants: Adverse Effects
404
Skeletal muscle relaxants are widely used for muscle paralysis and relieving pain following any muscle injury or stiffness. However, depending on the drug type, they can have adverse effects that range from mild to severe. Usually, nondepolarizing neuromuscular blockers have minimal side effects. For example, drugs like d-tubocurarine, cisatracurium, and rocuronium cause hypotension, whereas drugs like baclofen, when stopped abruptly, can lead to the recurrence of spastic conditions.
Unlike...
Unlike...
404


