在线适应性辐射疗法和机会成本
Kyra N McComas1, Adam Yock1, Kaleb Darrow1
1Department of Radiation Oncology, Vanderbilt University Medical Center, Nashville, Tennessee.
Advances in radiation oncology
|June 5, 2023
概括
在线适应性辐射疗法 (ART) 提高了治疗的准确性,但增加了每小部分的时间和成本. 这项研究发现,人工智能治疗需要额外的16分钟,每小部分的成本超过100美元,强调需要平衡效益与资源利用.
科学领域:
- 辐射瘤学 辐射瘤学
- 医学物理 医学物理
- 卫生经济学 卫生经济学
背景情况:
- 患者解剖学和瘤几何学的间断变化挑战了放射治疗的精度.
- 在线适应性辐射疗法 (ART) 通过治疗前的重新规划来解决这些变化.
- 评估ART对资源的影响对于其广泛采用至关重要.
研究的目的:
- 探索基于计算机断层扫描 (CT) 的在线ART的机会成本.
- 评估与在线ART相关的时间和人力资源需求.
- 确定ART的剂量测量效益是否证明了其相关成本.
主要方法:
- 基于时间驱动的基于活动的成本计算 (TDABC) 用于计算ART的成本.
- 分析了使用基于CT的在线ART治疗盆腔疾病治疗的415个部分的数据.
- 额外的时间被测量为形光束CT扫描之间的持续时间;用规划目标体积 (PTV) V100%差异来评估剂量效应.
主要成果:
- 每个适应分数需要平均额外的15.97分钟.
- 每个适应分数的平均最低成本为103.58美元.
- 在预定计划和调整计划之间观察到PTV V100%的平均剂量差异为15.8%.
结论:
- 在线ART减少了解剖学转换带来的不确定性,但增加了员工的时间和资源利用率.
- 实施像ART这样的先进技术需要仔细考虑时间,人力资源和机会成本.
- 需要进一步的研究来量化在线ART的毒性益处.
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