相关实验视频
Updated: Jul 27, 2025

07:44
A Porcine Model of Acute Autologous Pulmonary Embolism
Published on: September 6, 2024
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接种COVID-19疫苗可以预防肺栓塞吗?
Simona Tantillo1, Nicola Cilloni1, Martina Guarnera1
1Bologna, Italy Department of Anaesthesia, Intensive Care and EMS, Ospedale Maggiore "Carlo Alberto Pizzardi".
Journal of anesthesia, analgesia and critical care
|June 5, 2023
概括
接种COVID-19疫苗可能会保护住院患者免受肺栓塞 (PE). 在这项研究中,与未接种疫苗的患者相比,接种疫苗的患者显示PE患病率和疾病严重程度明显较低.
科学领域:
- 肺部医学 肺部医学
- 传染性疾病 传染性疾病
- 疫苗学 疫苗学 疫苗学
背景情况:
- 在COVID-19患者中,静脉血栓栓塞 (VTE) 的患病率有很大差异.
- 对住院COVID-19患者的肺栓塞 (PE) 疫苗接种的潜在保护作用仍未得到充分探索.
研究的目的:
- 为了调查和比较PE在接种疫苗的患病率与未接种疫苗的住院COVID-19患者.
主要方法:
- 在2021年11月至2022年1月期间进行的回顾性病例控制研究.
- 包括62名住院COVID-19患者,因为怀疑PE而接受胸部CT.
- 分析PE诊断,CT严重性得分 (CT-SS) 和患者人口统计 (年龄,并发症).
主要成果:
- 整体PE患病率为30.1% (19/62名患者).
- 与接种疫苗的患者相比 (11.1%),未接种疫苗的患者表现出明显更高的PE患病率 (45.7%),赔率比率 (OR) 为0.04.
- 未接种疫苗的患者也显示出更严重的CT成像发现 (CT-SS).
结论:
- 在COVID-19疫苗接种和住院患者的PE防护之间存在强烈的关联.
- 疫苗接种与该队列中PE的病率显著降低有关.
- 需要进一步的前性研究来确认接种疫苗对COVID-19相关的VTE的保护作用.
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