尾切除术前的低血与复杂尾炎的发病率增加有关
Lauren M Poston1, Tripp Leavitt2, Samantha Pope3
1Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA.
Surgery open science
|June 5, 2023
概括
手术前的低血与所有年龄组的复杂尾炎有关,特别是在儿科患者中. 这一发现表明,低血症可能有助于诊断尾炎的严重程度.
科学领域:
- 医学研究 医学研究
- 临床诊断 临床诊断 临床诊断
- 手术紧急情况.
背景情况:
- 急性尾炎是全球常见的手术紧急情况.
- 准确的手术前风险评估对于有效的治疗计划至关重要.
- 调查手术前低血与复杂尾炎的联系是必不可少的.
研究的目的:
- 为了检查术前低血和复杂的尾炎之间的关联.
- 为了在儿科,成人和老年人群中分层这种关联.
- 为了确定低血症是否可以作为尾炎严重程度的诊断标志物.
主要方法:
- 利用了TrinetX联合的EHR平台,拥有超过9000万个被删除身份的患者记录.
- 包括从2019年1月起接受尾切除术的患者,以及手术前的值.
- 将患者分层分为儿科,成人和老年人年龄组,比较低血量 (<135 mmol/L) 与正常血量 (135-145 mmol/L).
主要成果:
- 分析了来自61,245.5人的初始队列中的17546名倾向性得分匹配患者.
- 在所有年龄组中,手术前的低血症显著增加了复杂尾炎的几率.
- 患有低血的儿科患者的概率最高 (OR=2.91),其次是成年人 (OR=2.11) 和老年人 (OR=1.49).
结论:
- 在手术前的低血和复杂的尾炎之间存在显著的关联.
- 低血症可以作为一个有价值的预测标记在尾炎的诊断.
- 需要进一步的研究,将低血症纳入尾炎的临床决策工具中.
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