腹膜透析患者中肠球菌相关腹膜炎的临床特征
Jun Ni1, Liusha Zhou1, Hua Wang1
1Department of Nephrology, Hangzhou Hospital of Traditional Chinese Medicine (Hangzhou TCM Hospital Affiliated to Zhejiang Chinese Medical University), Hangzhou, Zhejiang, 310007, People's Republic of China.
Infection and drug resistance
|June 5, 2023
概括
腹腔透析 (PD) 患者的肠球菌腹腔炎很少见,但严重. 尽管万科米辛有效,但肠球菌感染的治疗失败率较高,预后较差,与其他常见的腹膜炎类型相比.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學.
- 传染性疾病 传染性疾病
- 临床微生物学 临床微生物学
背景情况:
- 腹膜炎是经过腹膜透析 (PD) 的患者的严重并发症.
- 菌种类是PD相关腹膜炎的不常见原因.
- 了解肠道炎的临床过程和结果对于患者的管理至关重要.
研究的目的:
- 在PD患者中研究肠球菌相关膜炎的临床特征和预后.
- 为了比较肠杆菌外周炎的结果与造成的Streptococcus和凝固酶阴性葡萄球菌 (CNS).
主要方法:
- 一项回顾性研究,将肠杆菌周周炎 (E组) 患者与与链球菌 (S组) 和中枢神经系统周炎相匹配的对照患者进行比较.
- 对临床特征,实验室发现,治疗反应和生存率的分析.
- 卡普兰-梅尔分析被用来评估累积存活率.
主要成果:
- 与其他组相比,Enterococcus peritonitis发作显示了更高的白细胞 (WBC) 和血液尿素 (BUN) 水平.
- 在肠球菌群中,治疗后白细胞计数仍然较高.
- 治愈率明显较低,累积存活率在患有肠球菌外周炎的患者中较差.
结论:
- 虽然很少见,但Enterococcus腹膜炎与PD患者的重大治疗挑战和较差的结果有关.
- 尽管对菌素敏感,但肠杆菌外周炎的失效率较高,预后较差,与链球菌和中枢神经系统外周炎相比.
- 需要进一步研究PD中肠炎的最佳管理策略.
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