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Two Flow Cytometric Approaches of NKG2D Ligand Surface Detection to Distinguish Stem Cells from Bulk Subpopulations in Acute Myeloid Leukemia
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可溶性NKG2D配体损害了CD8的作用.

Yi Zhang1, Feifei Luo2,3, Kuiran Dong1

  • 1Department of Pediatric Surgery, Children's Hospital of Fudan University, Shanghai 201102, P.R. China.

Oncology letters
|June 5, 2023
PubMed
概括

神经母细胞瘤使用可溶性NKG2D连接体 (NKG2DL) 来逃避T细胞免疫力. 阻止这些NKG2DL恢复了CD8+T细胞的功能,为神经母细胞瘤提供了一种新的免疫治疗策略.

关键词:
在NKG2D受体.一种分解蛋白和金属蛋白酶.神经母细胞瘤的神经母细胞瘤可溶性的NKG2DLDL.

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