在结直肠癌患者中的放射性物质
Riccardo Inchingolo1, Cesare Maino2, Roberto Cannella3
1Unit of Interventional Radiology, F. Miulli Hospital, Acquaviva delle Fonti 70021, Italy. riccardoin@hotmail.it.
World journal of gastroenterology
|June 5, 2023
概括
放射学是一种先进的成像分析,在识别高风险结肠直肠癌患者方面表现有前途. 需要进一步的研究来克服局限性,并将放射学纳入常规临床实践,以改善患者分层.
科学领域:
- 在瘤学瘤学.
- 放射学 放射学是一门学科.
- 人工智能的人工智能
背景情况:
- 结肠直肠癌的治疗依赖于手术和化疗,但预测复发风险具有挑战性.
- 放射学从肉眼看不见的放射图像中提取定量数据,进行高级分析.
- 人工智能算法可以分析放射学数据,以了解瘤生物学,并开发成像生物标志物.
研究的目的:
- 探索放射学在瘤学,特别是结肠直肠癌中不断扩大的作用.
- 审查放射学在预测转移,基因突变和治疗反应方面的应用.
- 评估放射学在识别高风险结肠直肠癌患者以进行量身定制治疗方面的潜力.
主要方法:
- 使用基于计算机的自动化技术分析放射图像 (CT,MRI,PET/CT) 的定量特征.
- 开发放射学特征和模型,包括用于分析随时间变化的三角洲放射学.
- 专注于基于MRI的放射学,用于预测直肠癌中的淋巴结转移.
主要成果:
- 使用CT图像开发了放射学签名,用于预测淋巴结转移和基因突变.
- 基于MRI的放射学模型显示了在直肠癌中淋巴结转移的术前预测的潜力.
- 在各种结直肠癌背景下,正在探索放射学以预测存活率和评估治疗反应.
结论:
- 放射学为识别高风险结直肠癌患者和改善疾病管理提供了一个有前途的工具.
- 尽管有潜力,但放射学面临着阻碍其日常临床应用的挑战.
- 进一步的研究是必要的,以验证放射学性能,并促进其整合到临床实践患者分层.
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