在成年人中多聚菌炎/皮肤菌炎的失声症
Hiromi Nagano1, Hayato Matsumoto1, Yuichi Kurono1
1Department of Otolaryngology Head and Neck Surgery, Kagoshima University Graduate School of Medical and Dental Sciences, 8-35-1 Sakuragaoka, Kagoshima, 890-8520 Japan.
概括
临床听力障碍,以声带白色病变为特征,会影响患有多质神经炎 (PM) 和皮质神经炎 (DM) 的患者. 观察到喉炎症,治疗后症状有所改善.
科学领域:
- 类风湿病学 类风湿病学
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 病理学 病理学 病理学
背景情况:
- 多髓炎 (PM) 和皮肤肌炎 (DM) 是一种炎症性肌肉病变.
- 失声症可能是这些疾病的临床表现.
- 在PM/DM中声带的参与尚未得到广泛研究.
研究的目的:
- 在被诊断患有多质神经炎 (PM) 或皮肤神经炎 (DM) 的患者中调查临床失声症.
- 描述PM/DM患者中与失声症相关的喉发现和组织病理特征.
主要方法:
- 对21名患有PM/DM的日本患者进行了回顾性队列研究.
- 通过喉腔镜检查评估的临床听力障碍.
- 喉白色病变的组织病理学检查.
主要成果:
- 8名患者 (38.1%) 报告有听障症.
- 在8名听力障碍患者中,有7名患有声带白色病变.
- 组织病理学揭示了自己膜炎症,纤维亡和炎症细胞透.
- 症状随着治疗而有所改善.
结论:
- 失声症是PM/DM患者的相关临床症状.
- 喉白色病变与特定的组织病理学发现与PM/DM的音障有关.
- 治疗可以缓解这些喉表现.
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