甲状腺结节和恶性病变的趋势:在第三级护理中心进行了一项为期两年的回顾性研究
Ruma Guha1,2, Sonali Jana1,2, Arpan Biswas1,2
1Department of ENT and Head and Neck Surgery, Calcutta National Medical College and Hospital, 32, Gorachand Road, Kolkata, 700014 India.
概括
这项研究调查了西孟加拉邦甲状腺癌的发生情况,发现22.91%的甲状腺结节是恶性,主要是乳头癌. 增加的TSH水平和3-5年的胀持续时间与更高的恶性瘤风险有关.
科学领域:
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 内分泌学 在内分泌学.
- 在瘤学瘤学.
背景情况:
- 甲状腺结节很常见,在全球范围内,差异化甲状腺癌的发病率正在增加.
- 有限的数据存在于西孟加拉州的结节中的甲状腺癌发生情况.
- 这项研究解决了当地流行病学数据的需求.
研究的目的:
- 为了确定西孟加拉州甲状腺结节患者甲状腺癌的发病率.
- 分析癌症发生与患者/结节特征之间的关联.
- 为了评估成像和细胞学的诊断性能.
主要方法:
- 对96名患有甲状腺结节的患者进行了回顾性审查,这些患者接受了USG,FNAC和手术.
- 收集的数据:患者人口统计学,胀持续时间,TSH水平,结节特征 (大小,数量),FNAC贝塞斯达分类和TIRADS评分.
- 对癌症发生的分析以及与临床和超声波发现的相关性.
主要成果:
- 总体恶性瘤发病率为22.91%,乳头癌是最常见的.
- 观察到更高的恶性瘤发病率,胀持续时间为3-5年 (50%) 和提升的TSH水平 (60%).
- 大小为1-2厘米的结节显示出最高的风险;贝塞斯达V和VI分别有100%和75%的恶性瘤率.
结论:
- 西孟加拉邦的甲状腺节块具有显著的癌症发病率 (22.91%).
- 提升的TSH和较长的胀持续时间是潜在的危险因素.
- USG (TIRADS) 和FNAC (Bethesda) 对于风险分层和诊断至关重要.
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