甲状腺结核的诊断和管理指南:我们的经验和系统审查
Poras Chaudhary1, Utsav Bhadana1, Anish Anand1
1Department of General Surgery, Atal Bihari Vajpayee Institute of Medical Sciences and Dr Ram Manohar Lohia Hopital, New Delhi, India.
概括
由于非特异性症状,甲状腺结核病的诊断具有挑战性. 基因病理学和精细针吸收细胞学 (FNAC) 与PCR测定是关键的,抗结核治疗 (ATT) 是主要的管理.
科学领域:
- 内分泌学 在内分泌学.
- 传染性疾病 传染性疾病
- 病理学 病理学 病理学
背景情况:
- 甲状腺结核病呈现出模糊的临床症状,使诊断和治疗复杂化.
- 有效的管理策略需要对诊断方式和治疗选择有充分的了解.
研究的目的:
- 审查甲状腺结核病的英语文献,以改善诊断和管理指南.
- 介绍三个案例研究,以说明临床经验.
主要方法:
- 从1950年到2019年,在PubMed和Medline进行了系统的文献搜索.
- 遵守系统审查和元分析 (PRISMA) 准则的首选报告项目.
- 包括13个相关手稿,包括7个案例系列和6个文献评论.
主要成果:
- 组织病理学检查是最终的诊断方法.
- 精细针吸收细胞学 (FNAC) 是首选的诊断研究,聚合酶链反应 (PCR) 试验提高了其灵敏度.
- 文献审查确定了关键的诊断和治疗方法.
结论:
- 直接组织病理学是诊断甲状腺结核病的黄金标准.
- 结合PCR分析的FNAC提供了高的诊断准确性.
- 标准抗结核治疗 (ATT) 建议在单独的病例中持续6个月,在扩散的疾病中延长至12个月;在治疗失败或的情况下,手术是保留的.
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