斯特多性脑膜炎和脑内血管病变
Garima Upreti1,2, Khevna Rathod1
1Department of Otorhinolaryngology and Head-Neck Surgery, Pandit Deendayal Upadhyay Medical College, Rajkot, Gujarat India.
疹病毒 (Varicella zoster virus,简称VZV) 在一个病人身上引起了脑多神经病变和内动脉血管病变. 诊断涉及VZV抗体在血清和CSF,尽管负的PCR.
科学领域:
- 神经学 神经学
- 传染性疾病 传染性疾病
- 血管神经学 血管神经学
背景情况:
- 麻疹病毒 (Varicella zoster virus,简称VZV) 可以导致神经系统并发症.
- 神经干扰和血管病变是VZV的罕见表现.
研究的目的:
- 报告一种VZV诱导的头骨多神经病变和内血管病变的病例.
- 要突出诊断挑战和管理这种罕见的条件.
主要方法:
- 一个45岁的女性患者的病例报告.
- 临床检查,对比脑部MRI,血清和脑液VZV IgG抗体检测,以及脑液VZV DNA PCR.
主要成果:
- 患者出现了状皮疹,神经 (V,VI,VII,VIII,IX,X),以及左侧内动脉狭窄.
- 血清和脑液中VZVIgG抗体的升高证实了VZV感染;脑液VZVPCR呈阴性.
结论:
- 非典型的VZV呈现会导致骨多神经病变和血管病变.
- 诊断可能具有挑战性,需要血清学确认.
- 神经功能的不良预后需要多学科的方法.
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