时机的区别是什么:皮质醇对情绪调节神经支的皮质醇影响
Dong-Ni Pan1,2,3, Valerie L Jentsch2, Katja Langer2
1School of Psychology, Beijing Language and Culture University, Beijing, 100083, China.
Neurobiology of stress
|June 5, 2023
概括
压力激素皮质醇随着时间的推移,会对情绪调节产生不同的影响. 快速效应阻碍,而缓慢效应改善,负面情绪管理的能力,帮助适应压力.
科学领域:
- 神经科学是一个神经科学.
- 心理学 心理学 心理学
- 内分泌学 在内分泌学.
背景情况:
- 情绪调节对于心理健康至关重要.
- 皮质醇 (压力激素) 通过非基因组和基因组途径对情绪调节的时间效应尚未完全理解.
研究的目的:
- 为了研究皮质醇对认知情绪调节的动态,时间依赖的影响.
- 区分快速 (非基因组) 和慢 (基因组) 皮质醇对情绪反应和神经活动的作用.
主要方法:
- 随机,双盲,安慰剂控制的神经成像研究,包括105名参与者.
- 在认知重新评估任务之前,在30分钟 (快速) 或90分钟 (缓慢) 服用皮质素 (皮质醇) 或安慰剂.
- 情绪反应和神经成像 (fMRI) 的行为评估,以测量大脑激活和功能连接.
主要成果:
- 在行为上,皮质醇最初减少了,但后来增加了对负面刺激的情绪反应.
- 皮质醇的缓慢效应改善了负面情绪的下调,与快速效应不同.
- 杏仁体和背侧前额叶皮质的神经活动及其连接性,显示与皮质醇的时间依赖性变化,表明最初无效,后来改善了情绪调节.
结论:
- 皮质醇对情绪调节产生时间依赖的影响,从最初无效的控制转向后来的有效控制.
- 这些动态皮质醇效应在适应和从压力经历中恢复方面发挥着作用.
- 了解这些时间动态对于心理健康干预至关重要.
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