血糖控制及其与2型糖尿病患者睡眠质量和持续时间的关联
Yadelew Yimer Shibabaw1, Tadesse Asmamaw Dejenie1, Kibur Hunie Tesfa1
1Department of Biochemistry, School of Medicine, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.
Metabolism open
|June 5, 2023
概括
2型糖尿病的低血糖控制与睡眠问题有关. 这项研究发现,睡眠质量差,睡眠时间短或长,以及阻塞性睡眠呼吸暂停的风险较低,与埃塞俄比亚患者的血糖控制较差有关.
科学领域:
- 内分泌学 在内分泌学.
- 代谢健康 代谢健康
- 睡眠医学 睡眠医学
背景情况:
- 低血糖控制仍然是2型糖尿病患者 (T2DM) 的重大挑战.
- 睡眠障碍会扰乱内分泌和代谢功能,可能通过激素和交感神经系统途径影响葡萄糖代谢.
- 埃塞俄比亚T2DM患者的睡眠模式和血糖控制之间的关联以前没有被调查过.
研究的目的:
- 为了评估T2DM患者的血糖控制水平.
- 确定T2DM患者的睡眠质量,睡眠持续时间,午睡习惯和血糖控制之间的关系.
- 在埃塞俄比亚西北部的一个特定医院环境中调查这些关联.
主要方法:
- 进行了一项基于机构的横截面研究,涉及407名T2DM患者.
- 测量了禁食血糖水平,以评估血糖控制.
- 使用匹兹堡睡眠质量指数评估睡眠质量,使用STOP-BANG问卷评估阻塞性睡眠呼吸暂停 (OSA) 风险.
主要成果:
- 超过一半 (54.05%) 的参与者表现出不良的血糖控制.
- 与低血糖控制显著相关的因素包括女性性别,睡眠质量差,睡眠时间短 (<6小时),睡眠时间长 (>8小时).
- 较低的OSA风险也与较差的血糖控制有关,而中等风险与高风险相比显示出保护作用.
结论:
- 在研究的T2DM患者群体中观察到低血糖控制的高患病率.
- 睡眠质量差,睡眠时间异常 (短时间和长时间),以及OSA风险降低与血糖控制受损有关.
- 建议强调良好的睡眠质量和适当的睡眠持续时间的重要性,以保持T2DM患者的最佳血糖控制.
相关概念视频
Diabetes Mellitus: Type 2 and Gestational
2.6K
Type 2 diabetes, characterized by insulin resistance, arises when the insulin receptors on cells lose responsiveness to insulin, diminishing the cell's capacity to take up glucose, resulting in elevated blood glucose levels. To receive a diagnosis of Type 2 diabetes, a series of blood glucose tests are necessary to assess whether the blood glucose falls within normal parameters. If the result is out of the normal range, a patient may be diagnosed as prediabetic or diabetic, depending on the...
2.6K
Diabetes: Management and Pharmacotherapy
319
The therapy for diabetes aims to alleviate hyperglycemia-related symptoms, prevent acute metabolic decompensation, and reduce chronic end-organ complications. Glycemic control is evaluated through short-term (self-monitoring, continuous glucose monitoring) and long-term (A1c, fructosamine) metrics, enabling near real-time tracking of blood glucose levels and reflecting glycemic control over specific time frames.
Insulin remains the cornerstone of treatment for most patients with type 1 and many...
Insulin remains the cornerstone of treatment for most patients with type 1 and many...
319
Diabetes: Symptoms, Diagnosis, and Complications
605
For most patients, experiencing several weeks of polyuria, polydipsia, fatigue, and significant weight loss may indicate the presence of diabetes. Furthermore, adults displaying the phenotypic appearance of type 2 diabetes (particularly those who are obese and not initially insulin-requiring), may have islet cell autoantibodies, suggesting autoimmune-mediated β cell destruction and a diagnosis of latent autoimmune diabetes of adults (LADA). The categorization of glucose homeostasis is...
605
Diabetes Mellitus: Overview and Type I Subtype
2.8K
Diabetes mellitus is a chronic metabolic disorder characterized by high blood glucose levels due to inadequate insulin production, insulin resistance, or both. The condition affects millions worldwide and can significantly impact their health and quality of life.
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
2.8K
Substance Use Disorders Affecting Sleep
199
Substance use disorders involve a pattern of using drugs more extensively than intended and continuing use despite harmful consequences. This includes legal substances like alcohol and nicotine, as well as illegal drugs. These disorders often involve both physical and psychological dependence, reflecting compulsive use of substances that significantly alter thoughts, feelings, and behaviors, contributing to a major public health issue.
Understanding the concepts of physical dependence,...
Understanding the concepts of physical dependence,...
199
Carbohydrate Metabolism
11.3K
Carbohydrates are polymers composed of molecules containing atoms of carbon, hydrogen and oxygen. One gram of carbohydrate can provide four kilo-calories of energy, which makes it the most efficient instant energy source.
Starch accounts for approximately 60% of the carbohydrates consumed by humans. Since amylase enzymes cannot function in the stomach's acidic environment, starch can only be digested in the mouth and small intestine. Simple sugars are found naturally in milk and fruits in...
Starch accounts for approximately 60% of the carbohydrates consumed by humans. Since amylase enzymes cannot function in the stomach's acidic environment, starch can only be digested in the mouth and small intestine. Simple sugars are found naturally in milk and fruits in...
11.3K


