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一个皮肤病例.
Louis J Born1, Shealinna Ge2, Juris P Germanas2,3
1University of Maryland School of Medicine Baltimore Maryland USA.
Skin health and disease
|June 5, 2023
概括
一种菌Scedosporium apiospermum,可以在免疫受损的个体中引起严重感染. 这项研究详细介绍了第一次报告的风湿性关节炎患者使用Janus激酶抑制剂的皮肤感染,以及对类似病例的审查.
科学领域:
- 医学真菌学 医学真菌学
- 传染性疾病 传染性疾病
- 皮肤病学 皮肤病学
背景情况:
- Scedosporium apiospermum是一种在土壤和水中发现的真菌,偶尔会引起机会性感染.
- 它对免疫功能低下的患者构成风险,可能导致严重的全身疾病.
- 由于空气中的真菌子,在医院获得的感染也令人担忧.
研究的目的:
- 报告第一例皮肤Scedosporium apiospermum感染病例.
- 用 Janus 激酶抑制剂治疗的类风湿性关节炎患者描述这种感染.
- 从2003年到2022年审查Scedosporium apiospermum的皮肤表现.
主要方法:
- 一个患有类风湿性关节炎和Scedosporium apiospermum皮肤感染的患者的病例报告.
- 2003年至2022年间发表的皮肤Scedosporium apiospermum病例的文献综述.
主要成果:
- 一名患有类风湿性关节炎的患者接受了Janus激酶抑制剂治疗,患上了皮肤Scedosporium apiospermum感染.
- 审查发现了各种Scedosporium apiospermum感染的皮肤表现.
结论:
- 皮肤Scedosporium apiospermum感染是一种罕见但显著的机会性感染.
- 免疫功能低下的患者,包括那些服用Janus激酶抑制剂的患者,都处于危险之中.
- 对不同临床表现的认识对于及时诊断和治疗至关重要.
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