图像增强内镜用于结直肠腺瘤检测的有效性:一个多中心的随机试验
Zhi-Peng Qi1, En-Pan Xu1, Dong-Li He2
1Endoscopy Center, Zhongshan Hospital of Fudan University, Shanghai 200030, China.
World journal of gastrointestinal oncology
|June 5, 2023
概括
在中国人群中,图像增强内镜 (IEE) 与白光成像 (WLI) 相比,没有显著改善腺瘤检测率 (ADR). 然而,第二代窄带成像 (2G-NBI) 显示ADR显著增加.
科学领域:
- 胃肠病学 胃肠病学
- 内镜成像系统的成像
- 结肠直肠癌 预防 预防
背景情况:
- 在结肠镜检查期间改善腺瘤检测可以降低结肠直肠癌的风险.
- 图像增强内镜 (IEE) 在进一步提高腺瘤检测率 (ADR) 的有效性仍然存在争议.
研究的目的:
- 为了比较IEE与传统白光成像 (WLI) 在检测和识别结直肠腺瘤方面的有效性.
- 评估不同IEE模式,包括狭带成像 (NBI) 对腺瘤检测的影响.
主要方法:
- 一个多中心,随机,受控试验,涉及4211名参与者在中国 (2019年9月 - 2021年4月).
- 患者被随机分配到IEE组 (进入时的WLI,退出时的IEE) 或WLI组 (进入和退出时的WLI).
- 主要结局是ADR;次要结局包括聚检测率 (PDR) 和每次结肠镜检测的腺瘤.
主要成果:
- 在IEE和WLI组之间的ADR没有显著差异 (24.0%与21.8%,P = 0.09).
- 在IEE组中,PDR明显高于IEE组 (41.7%),而不是WLI组 (36.1%,P = 0.01).
- 小组分析显示,与WLI相比,第二代窄带成像 (2G-NBI) 显著增加了ADR (27.0%对21.8%,P = 0.01).
结论:
- 在研究的中国人群中,IEE与WLI相比,并没有显著增加整体腺瘤检测率.
- 第二代窄带成像 (2G-NBI) 显示了腺瘤检测率的显著改善.
- 可能需要进一步的研究来优化IEE协议,以便在不同人群中更好地检测腺瘤.
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