微/纳米塑料对老鼠/老鼠模型的毒理学影响:系统性审查和元分析
Weijia Liu1,2, Bowen Zhang1, Qianqian Yao1
1Institute of Environment and Health, South China Hospital of Shenzhen University, Shenzhen, China.
Frontiers in public health
|June 5, 2023
概括
微/纳米塑料 (MNP) 显著影响小鼠和老鼠的生物终点,影响生殖和新陈代谢等系统. 男性的生殖功能对MNP毒性特别敏感.
科学领域:
- 环境毒理学环境毒理学
- 哺乳动物毒理学
- 生态毒理学 生态毒理学
背景情况:
- 微/纳米塑料 (MNP) 是广泛存在的环境污染物,已知有毒效应.
- 像老鼠和大鼠这样的哺乳动物模型对于研究MNP毒性至关重要.
- 缺乏对MNP对这些模型的毒性影响的系统总结.
结论:
- 许多MNP的毒性受各种因素的影响,包括大小,聚合物类型,度,暴露时间和动物的性别.
- 研究结果提供了关于MNP对人类健康风险的见解.
- 需要对分子机制和长期积累效应进行进一步的研究.
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