功能性近红外光谱神经反的背侧前额皮质增强人类的空间工作记忆
Keshuang Li1, Jinhao Yang1, Benjamin Becker2
1East China Normal University, School of Psychology and Cognitive Science, Affiliated Mental Health Center, Shanghai Key Laboratory of Mental Health and Psychological Crisis Intervention, Shanghai, China.
Neurophotonics
|June 5, 2023
概括
这项研究表明,功能近红外光谱神经反 (fNIRS-NF) 训练可以通过增强背侧前额皮层 (DLPFC) 激活来改善空间工作记忆 (SWM) 和注意力. 这些改善维持了一周.
科学领域:
- 神经科学是一个神经科学.
- 认知心理学 认知心理学
- 生物医学工程 生物医学工程
背景情况:
- 空间工作记忆 (SWM) 对于日常运作至关重要,并且在衰老和精神健康障碍中经常受到损害.
- 背侧前额皮层 (DLPFC) 激活失调与SWM缺陷密切相关.
研究的目的:
- 评估功能近红外光谱神经反 (fNIRS-NF) 培训的可行性和维护,以加强SWM.
- 研究实时fNIRS-NF对健康个体DLPFC激活的影响.
主要方法:
- 一个随机的模拟控制的,与60名健康参与者之间的实验对象设计.
- fNIRS-NF培训针对DLPFC,以SWM和注意力表现为主要结果.
- 由作者开发的实时fNIRS-NF平台.
主要成果:
- 与虚假神经反相比,fNIRS-NF显著增加了DLPFC的激活.
- 在实验小组中观察到增强的前侧双脚连接.
- 参与者在SWM和注意力方面表现出显著的改善,维持了一周.
- 增加DLPFC激活介导了fNIRS-NF对SWM的积极影响.
结论:
- 通过fNIRS-NF对DLPFC激活的自我调节是改善SWM的可行和有效的干预措施.
- 在SWM观察到的改善是持久的,并表明潜在的更广泛的临床应用.
- fNIRS-NF为非侵入性神经调节提供了一个有希望的途径,以增强认知功能.
相关概念视频
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