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相关概念视频

Electric Dipoles and Dipole Moment01:30

Electric Dipoles and Dipole Moment

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Consider two charges of equal magnitude but opposite signs. If they cannot be separated by an external electric field, the system is called a permanent dipole. For example, the water molecule is a dipole, making it a good solvent.
Theoretically, studying electric dipoles leads to understanding why the resultant electric forces around us are weak. Since electric forces are strong, remnant net charges are rare. Hence, the interaction between dipoles helps us understand electrical interactions in...
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Maximum Deflection01:13

Maximum Deflection

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When analyzing beams under unsymmetrical loads, such as a train moving on a bridge, it is crucial to accurately determine the points of maximum stress and deflection. The process involves identifying the maximum deflection of the beam, which may not always occur at its midpoint due to the uneven distribution of the load.
The maximum deflection occurs at a specific point, known as point O, where the tangent to the deflection curve is horizontal. To find point O, the slope of the tangent at any...
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Induced Electric Dipoles01:28

Induced Electric Dipoles

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A permanent electric dipole orients itself along an external electric field. This rotation can be quantified by defining the potential energy because the external torque does work in rotating it. Then, the potential energy is minimum at the parallel configuration and maximum at the antiparallel configuration. While the former is a stable equilibrium, the latter is an unstable equilibrium.
Since the absolute value of potential energy holds no physical meaning, its zero value can be chosen as per...
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Polymers: Molecular Weight Distribution01:10

Polymers: Molecular Weight Distribution

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For any given polymer, the weight average molecular weight (Mw) is higher than, if not equal to, the number average molecular weight (Mn). The only situation in which the weight average molecular weight and the number average molecular weight are equal is when a polymer consists only of chains with equal molecular weight. However, this never happens in a synthetic polymer, since it is difficult to control the polymerization process up to a molecular level with accuracy to a hundred percent.
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Quantifying and Rejecting Outliers: The Grubbs Test01:02

Quantifying and Rejecting Outliers: The Grubbs Test

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Sometimes, a data set can have a recorded numerical observation that greatly  deviates from the rest of the data. Assuming that the data is normally distributed, a statistical method called the Grubbs test can be used to determine whether the observation is truly an outlier.  To perform a two-tailed Grubbs test, first, calculate the absolute difference between the outlier and the mean. Then, calculate the ratio between this difference and the standard deviation of the sample. This...
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Divergence and Curl01:15

Divergence and Curl

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The divergence of a vector field at a point is the net outward flow of the flux out of a small volume through a closed surface enclosing the volume, as the volume tends to zero. More practically, divergence measures how much a vector field spreads out or diverges from a given point. For an outgoing flux, conventionally, the divergence is positive. The diverging point is often called the "source" of the field. Meanwhile, the negative divergence of a vector field at a point means that the...
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相关实验视频

Updated: Jul 27, 2025

Synthesis of Cyclic Polymers and Characterization of Their Diffusive Motion in the Melt State at the Single Molecule Level
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Synthesis of Cyclic Polymers and Characterization of Their Diffusive Motion in the Melt State at the Single Molecule Level

Published on: September 26, 2016

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最高的达菲 (Duffy) 在

Sylvia Armstrong-Fisher1, Stan Urbaniak1, Arian Karimi Rouzbahani2,3

  • 1Division of Applied Medicine, Institute of Medical Sciences University of Aberdeen Aberdeen UK.

Health science reports
|June 5, 2023
PubMed
概括

与减少Duffy抗原表达相关的FYX等位基因在5.41%的苏格兰献血者中被发现. 它的估计频率为0.0270%,高于之前报告的,影响了达菲血型的理解.

关键词:
珠子芯片微阵列微阵列达菲血型是达菲的血型.在FYX代基因组中,苏格兰人口 苏格兰人口.

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Single Synapse Indicators of Glutamate Release and Uptake in Acute Brain Slices from Normal and Huntington Mice
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相关实验视频

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科学领域:

  • 血液学 血液学 血液学
  • 遗传学 是一个遗传学.
  • 免疫学 免疫学 免疫学

背景情况:

  • 达菲 (FY) 血型系统具有关键抗原Fya和Fyb.
  • FYX表型源于FYB突变,导致达菲蛋白的不稳定性和抗原表达的减少.

研究的目的:

  • 为了确定苏格兰人口中的FYX等位基因频率.
  • 为了有助于对达菲血型变异的理解.

主要方法:

  • 对222个献血者样本进行血清和分子检查.
  • 使用血凝结和BeadChip微阵列方法进行表型和基因型鉴定.
  • 对于不一致的结果和达菲DNA测序的确认测试.

主要成果:

  • 达菲表型Fya+,Fya+b+和Fyb+的发生率分别为17.57%,42.79%和39.64%.
  • 基因型频率分别为FYA/FYA (14.41%),FYA/FYB (45.95%),以及FYB/FYB (39.64%).
  • 在12个样本 (5.41%) 中确定了FYX等位基因.

结论:

  • 据估计,苏格兰人口中的FYX等位基因频率为0.0270%.
  • 这种频率高于以前记录的,这表明该等位基因存在显著的存在.