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使用传感器进行连续的pH监测,用于早期检测静脉漏

Michelle Huynh^1,2, Ricky Tjandra¹, Nour Helwa¹

¹FluidAI Medical, Kitchener, ON, Canada.

Frontiers in medical technology

|June 5, 2023

概括

一种基于聚氨的新型pH传感器可以持续监测手术排水液,以便在减肥手术后及早检测出动脉泄漏 (AL). 这种直线传感器在10分钟内检测到pH值的变化,从而降低了患者的发病率和医疗费用.

科学领域:

生物医学工程生物医学工程
手术创新在外科创新.
医学诊断医学诊断医学诊断

背景情况:

解剖漏 (AL) 是低体重手术后的严重术后并发症,通常导致诊断延迟,患者发病率增加和医疗保健成本显著增加.
目前用于检测AL的方法依赖于反应性诊断,需要大量的临床医生资源和时间,这可能会加剧患者的结果.
虽然pH值是已知的AL生物标志物,但现有的检测方法资源密集,缺乏持续监测能力.

研究的目的:

开发和评估一种基于聚氨 (PANI) 的新型pH传感器,用于实时,持续监测腹液.
评估传感器在检测局部pH值变化时的有效性,这些变化表明在模拟的外科手术环境中存在解剖漏洞.
探索这项技术的潜力,以实现早期发现AL,从而减少患者的发病率和医疗负担.

主要方法:

一个基于聚氨 (PANI) 的pH传感器被设计用于在线连接到手术排水道.
使用PANI传感器测量了两头猪的腹膜液的基线pH值,并与标准基板pH值探针进行验证.
在模拟的胃泄漏过程中,PANI传感器用于连续监测腹内液 pH.

主要成果:

基于PANI的pH传感器成功测量了猪的腹膜液的基线pH值,与台式探针相对应得很好.
通过线内传感器进行持续监测,在模拟胃泄漏诱导后10分钟内检测到排水pH值的显著局部变化.
传感器展示了对腹膜分泌物中的恒常性pH值变化实时响应.

结论:

基于PANI的直线pH传感器提供了一个有前途的解决方案,用于持续实时监测腹膜分泌物.
这项技术有潜力显著降低在腹腔外科手术后检测门泄漏 (AL) 的时间.
成功的临床实施可能会改善患者的治疗结果,并减少与胃泄漏相关的经济负担.

关键词:

帕尼·帕尼 (PANI PANI) 是一个名字.静体泄漏发生在静体早期检测早期检测胃泄漏是因为胃泄漏.它们的pH值为pH.

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