在患有麻风和艾滋病毒的患者中,人体测量变量与肌肉力量之间的相关性
Diego Vinícius da Costa Novais1, Mariana Garcia Borges do Nascimento1, Geovanna Lemos Lopes1
1From the Núcleo de Medicina Tropical, Universidade Federal do Pará (UFPA), Belém, Pará, Brazil.
Indian journal of dermatology
|June 5, 2023
概括
与人类免疫缺陷病毒 (HIV) 和麻风的同时感染会比单独感染的任何一种疾病造成更大的运动损伤. 这种结合的神经影响会影响肌肉的强度和灵敏度,给患者护理带来重大挑战.
科学领域:
- 神经学 神经学
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
背景情况:
- 周围神经疾病,包括由艾滋病毒和麻风引起的疾病,可以导致严重的身体残疾.
- 神经损伤是艾滋病毒感染和麻风的已知并发症.
- 艾滋病毒和麻风的同时感染给患者管理和医疗保健带来了独特而复杂的挑战.
研究的目的:
- 为了研究和比较艾滋病毒和麻风联合感染的患者与那些单独感染艾滋病毒或麻风的患者的运动变化.
- 检查这些患者群体中运动缺陷与临床/人类学特征之间的关系.
主要方法:
- 一项涉及90名参与者的横截面研究,分为三个平等的组:艾滋病毒/艾滋病,麻风和艾滋病毒/麻风.
- 评估包括肌肉强度,上肢耐力,手掌印记压力 (数字动力计) 和人类测量.
- 统计分析使用多重线性回归调整为性别和年龄.
主要成果:
- 艾滋病毒/麻风群体显示最高的平均体重指数;皮在不同组之间是可比的.
- 与艾滋病毒和麻风的同时感染与肌肉功能的更糟糕预后有关,这可以通过减少手掌打印压缩强度来证明.
- 较高的CD4计数和较短的抗逆转录病毒疗法持续时间与共同感染患者的肌肉强度和抵抗力较差相关.
结论:
- 与艾滋病毒和麻风共同感染的患者相比,与单独感染艾滋病毒或麻风的患者相比,他们会经历更严重的运动损伤.
- 艾滋病毒和麻风的累积神经效应可能有助于观察到的运动缺陷.
相关概念视频
01:31Pulmonary Tuberculosis III
383
Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:
The first classification is based on the development of the disease, and it includes the following categories:
383
01:28Pulmonary Tuberculosis II
281
Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
281
01:29Pulmonary Tuberculosis I
288
Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
288
01:28Pulmonary Tuberculosis V
214
Medical management of tuberculosis (TB) patients involves a comprehensive approach that includes diagnosis, treatment, and monitoring. The specific strategies can vary depending on the type of tuberculosis (latent or active), the patient's overall health status, and other considerations.
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the...
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the...
214
01:26Pulmonary Tuberculosis IV
175
Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
175
01:12Coefficient of Correlation
6.3K
The correlation coefficient, r, developed by Karl Pearson in the early 1900s, is numerical and provides a measure of strength and direction of the linear association between the independent variable x and the dependent variable y.
If you suspect a linear relationship between x and y, then r can measure how strong the linear relationship is.
What the VALUE of r tells us:
The value of r is always between –1 and +1: –1 ≤ r ≤ 1.
The size of the correlation r indicates the...
If you suspect a linear relationship between x and y, then r can measure how strong the linear relationship is.
What the VALUE of r tells us:
The value of r is always between –1 and +1: –1 ≤ r ≤ 1.
The size of the correlation r indicates the...
6.3K