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Pathophysiology of Diabetes01:20

Pathophysiology of Diabetes

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Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia. The four categories of diabetes are type 1 diabetes, type 2 diabetes, other specific types of diabetes, and gestational diabetes.
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
1.0K
Obesity01:24

Obesity

552
The Body Mass Index (BMI) is a numerical value derived from a person's weight and height, used to categorize individuals into weight ranges. It is calculated using the formula: weight in kilograms divided by height in meters squared. Obesity is a health condition characterized by excessive accumulation of adipose tissue that poses health risks, often diagnosed with a BMI ≥ 30. This excess fat storage occurs when surplus dietary calories are converted into triglycerides and stored in...
552
Diabetes Mellitus: Type 2 and Gestational01:22

Diabetes Mellitus: Type 2 and Gestational

2.6K
Type 2 diabetes, characterized by insulin resistance, arises when the insulin receptors on cells lose responsiveness to insulin, diminishing the cell's capacity to take up glucose, resulting in elevated blood glucose levels. To receive a diagnosis of Type 2 diabetes, a series of blood glucose tests are necessary to assess whether the blood glucose falls within normal parameters. If the result is out of the normal range, a patient may be diagnosed as prediabetic or diabetic, depending on the...
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Teratogenicity01:07

Teratogenicity

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The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...
2.5K
Anorexia Nervosa01:28

Anorexia Nervosa

155
Anorexia nervosa is a complex and severe eating disorder characterized by an intense fear of weight gain, an unrelenting pursuit of thinness, and a distorted body image. It often leads to dangerously low body weight relative to an individual's age and height. This disorder is marked by significant physical and psychological consequences, making it one of the most life-threatening psychiatric illnesses.
Symptoms and Physical Effects
Individuals with anorexia nervosa commonly exhibit extreme...
155
Stress Prevention and Stress Management Techniques IV01:26

Stress Prevention and Stress Management Techniques IV

50
Stress often leads to unhealthy habits like smoking, excessive drinking, and overeating, which offer short-term relief but ultimately increase long-term health risks. These behaviors create a cycle that temporarily lowers stress levels but can result in severe long-term health consequences. Breaking these habits is essential to reduce the risk of chronic diseases and improve overall well-being. Three primary changes that support better health include quitting smoking, reducing alcohol intake,...
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相关实验视频

Updated: Jul 27, 2025

Author Spotlight: Collecting the Brain and Serum from the Same Mice Fetus to Study Brain Tumor Development
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Author Spotlight: Collecting the Brain and Serum from the Same Mice Fetus to Study Brain Tumor Development

Published on: May 17, 2024

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孕产妇肥胖:围产阶段的影响

Julie Reed1, Sarah Case1, Asha Rijhsinghani2

  • 1School of Medicine, University of Washington, Seattle, WA, USA.

SAGE open medicine
|June 5, 2023
PubMed
概括
此摘要是机器生成的。

孕妇肥胖率正在上升,孕妇和婴儿在怀孕和分娩期间面临的风险增加. 本综述强调了对母亲和后代神经发育的重大健康影响.

关键词:
产科/妇科 产科/妇科孕产妇的肥胖症 孕产妇的肥胖症新生儿的结果.肥胖 肥胖 肥胖 肥胖 肥胖 肥胖 肥胖 肥胖怀孕 怀孕 怀孕 怀孕 怀孕妇女的健康妇女的健康

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A Primary Human Trophoblast Model to Study the Effect of Inflammation Associated with Maternal Obesity on Regulation of Autophagy in the Placenta
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A Primary Human Trophoblast Model to Study the Effect of Inflammation Associated with Maternal Obesity on Regulation of Autophagy in the Placenta

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Modeling Encephalopathy of Prematurity Using Prenatal Hypoxia-ischemia with Intra-amniotic Lipopolysaccharide in Rats
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Modeling Encephalopathy of Prematurity Using Prenatal Hypoxia-ischemia with Intra-amniotic Lipopolysaccharide in Rats

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相关实验视频

Last Updated: Jul 27, 2025

Author Spotlight: Collecting the Brain and Serum from the Same Mice Fetus to Study Brain Tumor Development
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Author Spotlight: Collecting the Brain and Serum from the Same Mice Fetus to Study Brain Tumor Development

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A Primary Human Trophoblast Model to Study the Effect of Inflammation Associated with Maternal Obesity on Regulation of Autophagy in the Placenta
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A Primary Human Trophoblast Model to Study the Effect of Inflammation Associated with Maternal Obesity on Regulation of Autophagy in the Placenta

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Modeling Encephalopathy of Prematurity Using Prenatal Hypoxia-ischemia with Intra-amniotic Lipopolysaccharide in Rats
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科学领域:

  • 产科和妇科 产科和妇科
  • 孕产妇和胎儿医学 孕产妇和胎儿医学
  • 公共卫生 公共卫生

背景情况:

  • 在过去的三十年中,超重和肥胖在一般人口和孕妇中的患病率上升.
  • 妊娠前增加的体重指数和过度的妊娠体重增加有助于孕产妇的肥胖.
  • 孕产妇肥胖与诸如胰岛素耐药性,妊娠引起的高血压和感染等并发性并发症有关.

研究的目的:

  • 审查母亲肥胖对怀孕结果的多方面的影响.
  • 检查母亲肥胖对胎儿发育和分娩的影响.
  • 探索母亲肥胖与后代长期神经发育结果之间的关联.

主要方法:

  • 对过去三十年发表的研究进行了全面的文献综述.
  • 对母亲妊娠前BMI,妊娠期体重增加和相关健康风险的数据分析.
  • 检查胎儿生长,分娩并发症,新生儿结果和后代神经发育轨迹.

主要成果:

  • 孕产妇的肥胖增加了胎儿异常,胎儿生长变化和不良分娩结果 (仪器化阴道分娩,剖腹产) 的风险.
  • 肥胖的母亲有更高的伴随性疾病和传染病的发病率.
  • 新生儿结局受到负面影响,包括出生体重增加,需要呼吸支持,以及缺氧缺血性脑病变的风险.

结论:

  • 孕产妇的肥胖在整个怀孕,分娩和产后存在重大风险.
  • 孕产妇肥胖与后代的神经发育不良结果之间存在强烈的关联.
  • 解决孕产妇肥胖问题对于改善孕产妇和儿童健康结果至关重要.