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在电治疗中模拟视野的影响电流流动模拟

Alexander Guillen¹, Christopher C Abbott², Zhi-De Deng³

¹Research and Development, Soterix Medical, Woodbridge, NJ, United States.

Frontiers in psychiatry

|June 5, 2023

概括

视野 (FOV) 显著影响电治疗 (ECT) 模拟. 双边 (BL) ECT模型比右边单边 (RUL) ECT对FOV限制更敏感,这表明全头MRI数据对于准确的BL模拟至关重要.

科学领域:

医疗成像医学成像
计算神经科学是一种神经科学.
神经调节是一种神经调节.

背景情况:

电疗法 (ECT) 的MRI引导前模型受到收集的视野 (FOV) 的限制.
在ECT模拟中使用不同的模型范围,可能会影响结果.
本研究研究了FOV对右侧单边 (RUL) 和双边 (BL) 电极放置的电场 (E-field) 分布的影响.

研究的目的:

检查不同磁共振成像 (MRI) 视野 (FOV) 范围对电治疗 (ECT) 模拟中的诱导电场 (E-field) 的影响.
为了比较右侧单边 (RUL) 和双边 (BL) 电极放置对FOV变化的灵敏度.
为了确定准确的ECT建模所需的最低FOV.

主要方法:

一个全身数据集被处理,以创建不同范围的模型,从头部到干.
相对误差 (RE) 是通过将每个程度的刺激强度与全身参考模型进行比较来计算的.
使用2D和3D空间图片可视化电子场分布并评估刺激指标.

主要成果:

双边 (BL) ECT模拟显示了较高的相对误差 (~50%) 与头部FOV,减少到~2%与部FOV.
右侧单边 (RUL) ECT模拟的相对误差较小 (~5%),上部头部FOV,降至0.28%的全头FOV.
BL刺激覆盖了更大的大脑体积,但仅限于头部,而RUL诱导的体积在更高的幅度时更大,特别是在考虑具有更大的FOV的BL模型中的电流损失时.

结论:

双边 (BL) ECT建模比右边单边 (RUL) 建模更容易受到视野 (FOV) 的限制.
对于BL ECT模拟,建议使用全头MRI数据,可能需要更大的FOV.
由于大脑体积刺激更大,BL ECT更有效的假设需要重新评估,考虑到FOV影响和潜在的电流损失.

关键词:

美国欧洲欧洲欧洲欧洲欧洲这就是为什么MRI是MRI.电疗法是一种电疗法.在某种程度上,这是一个很大的范围.人类头部模型模型模拟模拟是指一个模拟模拟.验证验证的时间

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