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烟草吸烟和双相情感障碍中自杀风险:一个系统审查
Jesús García-Jiménez1, Francisco José Gómez-Sierra1, Alicia Martínez-Hortelano2
1Department of Psychiatry, San Cecilio University Hospital, Granada, Spain.
Frontiers in psychiatry
|June 5, 2023
概括
这次审查发现了不一致的证据,表明在双相情感障碍 (BD) 患者中,吸烟与自杀风险有关. 由于研究的变异性,无法建立明确的关系,强调需要更好地评估和规划这些并发性疾病的治疗.
科学领域:
- 精神病学是一个精神病学.
- 心理健康研究 心理健康研究
- 流行病学 流行病学
背景情况:
- 双极性障碍 (BD) 是一种常见的慢性精神疾病,吸烟率高.
- 抑郁症与增加自杀风险有关,吸烟与一般人群的自杀行为有关.
研究的目的:
- 系统地审查有关双相情绪障碍患者吸烟和自杀行为之间的联系的证据.
主要方法:
- 一个全面的数据库搜索 (Medline,Embase,Cochrane,Scopus,Web of Science) 进行到2021年12月.
- 包括集中在BD患者的吸烟和自杀行为数据的研究,不包括那些仅涉及其他疾病的研究.
- 使用太华-纽卡斯尔尺度评估方法质量.
主要成果:
- 包括15篇文章 (7,395名参与者). 在BD中,有9人发现吸烟与自杀行为之间存在关联;有6人没有.
- 在测量自杀行为和烟草消费方面存在显著的变化.
- 大多数研究都有高偏差风险,只有两项被认为风险低.
结论:
- 由于研究异质性和方法限制,无法确定烟草使用与BD患者自杀风险之间的明确联系.
- 吸烟和自杀行为在BD中非常普遍,并对预后产生负面影响.
- 对吸烟习惯和自杀风险的系统评估对于 BD 中有效的治疗计划至关重要.
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