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Updated: Jun 21, 2026

Flat Mount Imaging of Mouse Skin and Its Application to the Analysis of Hair Follicle Patterning and Sensory Axon Morphology
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猪皮的单细胞转录基因图谱描述了解剖学位置异质性的特征

Qin Zou1, Rong Yuan2, Yu Zhang3

  • 1Department of Zoology, College of Life Science, Sichuan Agricultural University, Ya'an, China.

eLife
|June 5, 2023
PubMed
概括

这项研究揭示了不同身体部位的猪皮肤细胞中独特的基因表达,揭示了细胞专业化. 这些发现提高了对皮肤生物学和皮肤再生和移植的潜在应用的理解.

关键词:
细胞 细胞 细胞.细胞生物学 细胞生物学猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪皮肤 皮肤 皮肤

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Pleiotropy01:33

Pleiotropy

Pleiotropy is the phenomenon in which a single gene impacts multiple, seemingly unrelated phenotypic traits. For example, defects in the SOX10 gene cause Waardenburg Syndrome Type 4, or WS4, which can cause defects in pigmentation, hearing impairments, and an absence of intestinal contractions necessary for elimination. This diversity of phenotypes results from the expression pattern of SOX10 in early embryonic and fetal development. SOX10 is found in neural crest cells that form melanocytes,...