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Updated: Jul 9, 2026

Identification of Key Factors Regulating Self-renewal and Differentiation in EML Hematopoietic Precursor Cells by RNA-sequencing Analysis
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通过单细胞RNA测序来识别髓瘤溢出的进化机制

Zhengxu Sun1, Jiamei Ji1, Yating Li1

  • 1Department of Hematology, The First Affiliated Hospital of Nanjing Medical University, Jiangsu Province Hospital, Nanjing, China.

Blood advances
|June 5, 2023
PubMed
概括

骨髓瘤溢出 (ME) 涉及到外骨髓质多发性骨髓瘤 (MM) 的扩散. 研究人员确定了新型外骨髓起始细胞 (EMIC) 和LILRB4作为这种罕见癌症进展的关键驱动因素.

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相关概念视频

RNA-seq03:21

RNA-seq

RNA sequencing, or RNA-Seq, is a high-throughput sequencing technology used to study the transcriptome of a cell. Transcriptomics helps to interpret the functional elements of a genome and identify the molecular constituents of an organism. Additionally, it also helps in understanding the development of an organism and the occurrence of diseases. 
Before the discovery of RNA-seq, microarray-based methods and Sanger sequencing were used for transcriptome analysis. However, while microarray-based...