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Updated: Jul 27, 2025

Purification of Extracellular Trypanosomes, Including African, from Blood by Anion-Exchangers Diethylaminoethyl-cellulose Columns
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Purification of Extracellular Trypanosomes, Including African, from Blood by Anion-Exchangers Diethylaminoethyl-cellulose Columns

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两个含有蛋白质的冷震域触发了传染性Trypanosoma brucei的发展

Justin Y Toh1, Agathe Nkouawa1, Gang Dong2

  • 1Department of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, Connecticut, United States of America.

PLoS pathogens
|June 5, 2023
PubMed
概括

在Trypanosoma brucei中,两个冷冲击域 (CSD) 蛋白质对于产生传染性元循环寄生虫至关重要. 它们的N端域和核酸结合点对于这种发育过渡至关重要.

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Conservation of Protein Domains Over Different Proteins02:26

Conservation of Protein Domains Over Different Proteins

Protein domains are small structurally independent units that are part of a single amino acid chain.  Although these domains are often structurally independent, they may rely on synergistic effects to perform their functions as part of a larger protein. Protein domains may be conserved within the same organism, as well as across different organisms.
A limited set of protein domains often duplicate and recombine during evolution. These domains can be organized in different combinations to...
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