在大型急性缺血性中风中,将内血管血栓切除术添加到药物治疗中,在90d改善了功能
1University of Ottawa, Ottawa, Ontario, Canada (E.F.).
Annals of internal medicine
|June 5, 2023
概括
血管内血栓切除术是有效的治疗大缺血性中风在可挽救的大脑组织的患者. 与标准护理相比,这种治疗显著改善了功能结果.
科学领域:
- 神经学 神经学
- 干预心脏病学 干预心脏病学
- 神经外科 神经外科
背景情况:
- 大型缺血性中风需要快速有效的治疗,以防止严重的残疾.
- 血管内血栓切除术已经成为急性缺血性中风的有希望的干预措施.
- 血栓切除术在患有大血管封闭症的特定患者亚组中的有效性需要进一步澄清.
研究的目的:
- 评估内血管血栓切除术在患有大缺血性中风和可挽救脑组织证据的患者中的有效性和安全性.
主要方法:
- SELECT2研究是一项随机对照试验,涉及患有大血管封闭性缺血性中风的患者.
- 参与者被随机分配到接受内血管血栓切除术加标准医疗保健或仅接受标准医疗保健.
- 使用成像标准来选择具有大量可挽救的大脑组织的患者.
主要成果:
- 与仅仅医疗护理相比,内血管血栓切除术在90天后显著改善了功能结果.
- 血栓切除组的成功再输血率在血栓切除组中更高.
- 两组之间没有观察到症状性内出血率的显著差异.
结论:
- 血管内血栓切除术是一种安全有效的治疗选择的大型缺血性中风患者.
- 这项研究支持扩大血栓切除术的适用范围,包括患有大心脏梗塞和可挽救组织的患者.
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