淋巴细胞透和抗瘤作用由细胞毒性炎症蛋白质促进,其配方是自组装,仅由蛋白质组成的纳米粒子

Carlos Martínez-Torró1, Lorena Alba-Castellón2, Luis Miguel Carrasco-Díaz3

  • 1Institut de Biotecnologia i de Biomedicina, Universitat Autònoma de Barcelona, 08193 Bellaterra, Spain; CIBER de Bioingeniería, Biomateriales y Nanomedicina (CIBER-BBN), Universitat Autònoma de Barcelona, 08193 Bellaterra, Spain.

概括

工程气体皮质D (GSDMD) 和混合血统激酶域类蛋白质 (MLKL) 形成了针对瘤的纳米粒子. 这些新型药物通过招募免疫细胞来减少小鼠结肠直肠癌的大小,而不会产生全身毒性.

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