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对粘膜相关的不变T细胞对代谢物抗原识别的分子见解

Wael Awad1, Lisa Ciacchi1, James McCluskey2

  • 1Infection and Immunity Program and Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, Victoria 3800, Australia.

Current opinion in immunology
|June 5, 2023
PubMed
概括

由MR1分子呈现的小分子代谢物激活T细胞,这对于对微生物的免疫力,自身免疫力和癌症至关重要. 这些代谢物的化学修饰揭示了T细胞受体识别的洞察力.

关键词:
变化的代谢物 干在MAIT的免疫力.在MR1中,MRI是MRI.有MR1限制的T.代谢物的抗原是代谢物中的抗原.

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